{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T09:00:08Z","timestamp":1780563608283,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T00:00:00Z","timestamp":1452038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate defecation and micturition complaints in adults treated for sacrococcygeal teratoma (SCT) during childhood and to identify risk factors for soiling, urinary incontinence, and constipation beyond childhood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>Records of patients aged \u226518 treated for SCT during infancy in the Netherlands were retrospectively reviewed. Frequency and severity of soiling, constipation, and urinary incontinence were evaluated using questionnaires designed in line with the Krickenbeck classification. Problems during childhood were compared to outcomes at adult age in part of the cohort. Associations between patient\u2010 and disease\u2010related factors with complaints beyond childhood were analyzed with the chi\u2010square test or Fisher's exact test, when appropriate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 47 included patients (mean age 26.2 years, SD \u00b16.5), 49% reported at least one defecation or micturition complaint. Urinary incontinence was present in 30% and had a greater negative impact than soiling (24%). Ten patients (21%) reported constipation; five found this severely bothering. Three patients reported social restrictions due to defecation or micturition complaints (6.4%). While sex and tumor histology were not identified as risk factors, a tumor diameter of &gt;10 cm and Altman type I or type II SCT were associated with constipation during adulthood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>One\u2010third of the patients treated for SCT during childhood reported urinary and defecation problems beyond childhood. In only a minority of cases, these led to social restrictions. A greater tumor diameter was associated with a higher risk of constipation during adulthood. Prolonged surveillance strategies are advised for all patients with SCT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.25857","type":"journal-article","created":{"date-parts":[[2016,1,7]],"date-time":"2016-01-07T12:32:25Z","timestamp":1452169945000},"page":"690-694","source":"Crossref","is-referenced-by-count":21,"title":["Patient\u2010Reported Defecation and Micturition Problems Among Adults Treated for Sacrococcygeal Teratoma During Childhood\u2014The Need for New Surveillance Strategies"],"prefix":"10.1002","volume":"63","author":[{"given":"Marijke E.B.","family":"Kremer","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Maastricht University Medical Center  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joep P.M.","family":"Derikx","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Maastricht University Medical Center  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robertine","family":"van Baren","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery University Medical Center Groningen  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo A.","family":"Heij","sequence":"additional","affiliation":[{"name":"Pediatric Surgical Center of Amsterdam Emma Children's Hospital University Medical Center and VU Medical Center  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc H.W.A.","family":"Wijnen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery University Medical Center Nijmegen  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9 M.H.","family":"Wijnen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Sophia Children's Hospital Erasmus University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"van der Zee","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Wilhelmina Children's Hospital University Medical Center Utrecht  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest L.W.E.","family":"van Heurn","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Maastricht University Medical Center  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12211"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32832b41ee"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.01.050"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.22887"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00012-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(92)90197-F"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.10.066"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(93)90156-F"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306414"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00175838"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(74)80297-6"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.08.002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(94)90367-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(92)90394-M"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-307589"},{"key":"e_1_2_6_17_1","first-page":"358","article-title":"Sacral teratomas in childhood. 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