{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T04:04:06Z","timestamp":1774497846864,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,6,8]],"date-time":"2016-06-08T00:00:00Z","timestamp":1465344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Patients with common variable immunodeficiency (CVID) have a higher incidence of autoimmune disease, which may mark the disease onset; however, anemia secondary to pure red cell aplasia is an uncommon presenting feature. Here, we describe a case of CVID\u2010like humoral immune deficiency in a child who initially presented with red cell aplasia and ultimately developed progressive bone marrow failure. Although bone marrow transplantation (BMT) has been associated with high mortality in CVID, our patient was successfully treated with a matched sibling BMT and engrafted with &gt;98% donor chimerism and the development of normal antibody titers to diphtheria and tetanus toxoids.<\/jats:p>","DOI":"10.1002\/pbc.26092","type":"journal-article","created":{"date-parts":[[2016,6,8]],"date-time":"2016-06-08T13:40:04Z","timestamp":1465393204000},"page":"1856-1859","source":"Crossref","is-referenced-by-count":5,"title":["Bone marrow transplantation for CVID\u2010like humoral immune deficiency associated with red cell aplasia"],"prefix":"10.1002","volume":"63","author":[{"given":"Elias J.","family":"Sayour","sequence":"first","affiliation":[{"name":"UF Brain Tumor Immunotherapy Program, Preston A. Wells Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, Department of Neurosurgery University of Florida  Gainesville Florida"},{"name":"Division of Pediatric Hematology\u2010Oncology, Department of Pediatrics University of Florida  Gainesville Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talal","family":"Mousallem","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Pediatrics Wake Forest University School of Medicine  Winston Salem North Carolina"},{"name":"Division of Allergy\u2010Immunology Department of Pediatrics, and Department of Immunology, Duke University Medical Center  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Van Mater","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology, Department of Pediatrics Duke University Medical Center  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Endi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Patholgy Duke University Medical Center  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Martin","sequence":"additional","affiliation":[{"name":"Division of Pediatric Bone Marrow Transplantation, Department of Pediatrics Duke University Medical Center  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca H.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Division of Allergy\u2010Immunology Department of Pediatrics, and Department of Immunology, Duke University Medical Center  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond C.","family":"Barfield","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology, Department of Pediatrics Duke University Medical Center  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.02.039"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.11.029"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.12.3995"},{"issue":"4","key":"e_1_2_6_5_1","first-page":"285","article-title":"Therapy of pure red cell aplasia","volume":"28","author":"Marmont A.M.","year":"1991","journal-title":"Semin Hematol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.8.5074"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-11-321695"},{"issue":"5","key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1182\/blood.V90.5.2103","article-title":"Bone marrow contains virus\u2010specific cytotoxic T lymphocytes","volume":"90","author":"Slifka MK","year":"1997","journal-title":"Blood"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/86523"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2567.2003.01593.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.9-3-247"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05144.x"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.26092","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.26092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T15:13:48Z","timestamp":1695741228000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.26092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,8]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1002\/pbc.26092"],"URL":"https:\/\/doi.org\/10.1002\/pbc.26092","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,8]]}}}