{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T20:03:57Z","timestamp":1762459437295},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T00:00:00Z","timestamp":1476662400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T00:00:00Z","timestamp":1476662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"name":"Barretos Pediatric Cancer Center"},{"name":"Brazilian Research Council"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Blood Cancer"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1002\/pbc.26285","type":"journal-article","created":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T05:51:52Z","timestamp":1476683512000},"page":"e26285","source":"Crossref","is-referenced-by-count":13,"title":["Characteristics of the phenotypic abnormalities of bone marrow cells in childhood myelodysplastic syndromes and juvenile myelomonocytic leukemia"],"prefix":"10.1002","volume":"64","author":[{"given":"Anita F.","family":"Oliveira","sequence":"first","affiliation":[{"name":"Childrens\u2019 Cancer Hospital; Barretos Cancer Center; Barretos SP Brazil"},{"name":"Morphology\/Flow Cytometry Committee; Brazilian Cooperative Group of Pediatric Myelodysplastic Syndromes (BCG-MDS-PED); Barretos S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"Tansini","sequence":"additional","affiliation":[{"name":"Morphology\/Flow Cytometry Committee; Brazilian Cooperative Group of Pediatric Myelodysplastic Syndromes (BCG-MDS-PED); Barretos S\u00e3o Paulo Brazil"},{"name":"Diagnostic Laboratory of Barretos Cancer Center; Barretos S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel O.","family":"Vidal","sequence":"additional","affiliation":[{"name":"Diagnostic Laboratory of Barretos Cancer Center; Barretos S\u00e3o Paulo Brazil"},{"name":"Pediatric Oncology Laboratory; Molecular Oncology Research Center; Barretos Cancer Hospital; Barretos S\u00e3o Paulo Brazil"},{"name":"Molecular Biology Committee; Brazilian Cooperative Group of Pediatric Myelodysplastic Syndromes; Barretos S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz F.","family":"Lopes","sequence":"additional","affiliation":[{"name":"Childrens\u2019 Cancer Hospital; Barretos Cancer Center; Barretos SP Brazil"},{"name":"Chair of the Brazilian Cooperative Group of Pediatric Myelodysplastic Syndromes; Barretos S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konradin","family":"Metze","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences; University of Campinas; Campinas S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Lorand-Metze","sequence":"additional","affiliation":[{"name":"Morphology\/Flow Cytometry Committee; Brazilian Cooperative Group of Pediatric Myelodysplastic Syndromes (BCG-MDS-PED); Barretos S\u00e3o Paulo Brazil"},{"name":"Faculty of Medical Sciences; University of Campinas; Campinas S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,17]]},"reference":[{"key":"10.1002\/pbc.26285-BIB0001|pbc26285-cit-0001","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1038\/sj.leu.2402765","article-title":"A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases","volume":"17","author":"Hasle","year":"2003","journal-title":"Leukemia"},{"key":"10.1002\/pbc.26285-BIB0002|pbc26285-cit-0002","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1046\/j.1365-2141.2003.04361.x","article-title":"Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia in the UK: a population-based study of incidence and survival","volume":"121","author":"Passmore","year":"2003","journal-title":"Br J Haematol"},{"key":"10.1002\/pbc.26285-BIB0003|pbc26285-cit-0003","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1080\/088800199277182","article-title":"Childhood myelodysplastic syndromes in a Brazilian population","volume":"16","author":"Lopes","year":"1999","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1002\/pbc.26285-BIB0004|pbc26285-cit-0004","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.5858\/2007-131-1110-MSICAC","article-title":"Myelodysplastic syndromes in children","volume":"131","author":"Elghetany","year":"2007","journal-title":"Arch Pathol Lab Med"},{"key":"10.1002\/pbc.26285-BIB0005|pbc26285-cit-0005","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/j.1365-2559.2011.04156.x","article-title":"Morphological differentiation of severe aplastic anaemia from hypocellular refractory cytopenia of childhood: reproducibility of histopathological diagnostic criteria","volume":"61","author":"Baumann","year":"2012","journal-title":"Histopathology"},{"key":"10.1002\/pbc.26285-BIB0006|pbc26285-cit-0006","doi-asserted-by":"publisher","first-page":"2391","DOI":"10.1182\/blood-2016-03-643544","article-title":"The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia","volume":"127","author":"Arber","year":"2016","journal-title":"Blood"},{"key":"10.1002\/pbc.26285-BIB0007|pbc26285-cit-0007","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.3324\/haematol.2009.005801","article-title":"Standardization of flow cytometry in myelodysplastic syndromes: report from the first European LeukemiaNet working conference on flow cytometry in myelodysplastic syndromes","volume":"94","author":"de Loosdrecht","year":"2009","journal-title":"Haematologica"},{"key":"10.1002\/pbc.26285-BIB0008|pbc26285-cit-0008","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.leukres.2011.09.015","article-title":"Implementation of flow cytometry in the diagnostic work-up of myelodysplastic syndromes in a multicenter approach: report from the Dutch Working Party on Flow Cytometry in MDS","volume":"36","author":"Westers","year":"2012","journal-title":"Leuk Res"},{"key":"10.1002\/pbc.26285-BIB0009|pbc26285-cit-0009","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.leukres.2006.04.010","article-title":"Detection of hematopoietic maturation abnormalities by flow cytometry in myelodysplastic syndromes and its utility for the differential diagnosis with non-clonal disorders","volume":"31","author":"Lorand-Metze","year":"2007","journal-title":"Leuk Res"},{"key":"10.1002\/pbc.26285-BIB0010|pbc26285-cit-0010","doi-asserted-by":"publisher","first-page":"e81048","DOI":"10.1371\/journal.pone.0081048","article-title":"Immunophenotyping in myelodysplastic syndromes can add prognostic information to well-established and new clinical scores","volume":"8","author":"Reis-Alves","year":"2013","journal-title":"PLoS One"},{"key":"10.1002\/pbc.26285-BIB0011|pbc26285-cit-0011","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s13000-015-0259-3","article-title":"Improving the differential diagnosis between myelodysplastic syndromes and reactive peripheral cytopenias by multiparametric flow cytometry: the role of B-cell precursors","volume":"10","author":"Reis-Alves","year":"2015","journal-title":"Diagn Pathol"},{"key":"10.1002\/pbc.26285-BIB0012|pbc26285-cit-0012","doi-asserted-by":"publisher","first-page":"530","DOI":"10.4149\/neo_2010_06_530","article-title":"The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes","volume":"57","author":"Reis-Alves","year":"2010","journal-title":"Neoplasma"},{"key":"10.1002\/pbc.26285-BIB0013|pbc26285-cit-0013","doi-asserted-by":"publisher","first-page":"315","DOI":"10.3324\/haematol.2014.107706","article-title":"Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood","volume":"100","author":"Aalbers","year":"2015","journal-title":"Haematologica"},{"key":"10.1002\/pbc.26285-BIB0014|pbc26285-cit-0014","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1002\/pbc.21874","article-title":"Advanced pediatric myelodysplastic syndromes: can immunophenotypic characterization of blast cells be a diagnostic and prognostic tool?","volume":"52","author":"Veltroni","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"10.1002\/pbc.26285-BIB0015|pbc26285-cit-0015","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1038\/leu.2013.81","article-title":"Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood","volume":"27","author":"Aalbers","year":"2013","journal-title":"Leukemia"},{"key":"10.1002\/pbc.26285-BIB0016|pbc26285-cit-0016","doi-asserted-by":"publisher","first-page":"707","DOI":"10.3324\/haematol.2015.137711","article-title":"Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome","volume":"101","author":"Nov\u00e1kov\u00e1","year":"2016","journal-title":"Haematologica"},{"key":"10.1002\/pbc.26285-BIB0017|pbc26285-cit-0017","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3109\/10428190903370346","article-title":"Hematogones: a review and update","volume":"51","author":"Sevilla","year":"2010","journal-title":"Leuk Lymphoma"},{"key":"10.1002\/pbc.26285-BIB0018|pbc26285-cit-0018","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1002\/cyto.b.21085","article-title":"Significant changes in the composition of the precursor B-cell compartment in children less than 2 years old","volume":"84B","author":"Piatosa","year":"2013","journal-title":"Cytometry B"},{"key":"10.1002\/pbc.26285-BIB0019|pbc26285-cit-0019","doi-asserted-by":"publisher","first-page":"1404","DOI":"10.1016\/j.leukres.2013.07.024","article-title":"Hematogones: an overview","volume":"37","author":"Chantepie","year":"2013","journal-title":"Leuk Res"},{"key":"10.1002\/pbc.26285-BIB0020|pbc26285-cit-0020","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1046\/j.1365-2303.1999.00145.x","article-title":"Argyrophilic nucleolar organizer region (AgNOR) technique: a helpful tool for differential diagnosis in urinary cytology","volume":"10","author":"Cia","year":"1999","journal-title":"Cytopathology"},{"key":"10.1002\/pbc.26285-BIB0021|pbc26285-cit-0021","first-page":"564","article-title":"The differential diagnosis between aplastic anemia and hypocellular myelodysplasia in patients with pancytopenia","volume":"84","author":"Lorand-Metze","year":"1999","journal-title":"Haematologica"},{"key":"10.1002\/pbc.26285-BIB0022|pbc26285-cit-0022","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1136\/jmg.2006.045906","article-title":"Guidelines for the diagnosis and management of individuals with neurofibromatosis 1","volume":"44","author":"Ferner","year":"2007","journal-title":"J Med Genet"},{"key":"10.1002\/pbc.26285-BIB0023|pbc26285-cit-0023","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/S0145-2126(01)00187-4","article-title":"The Brazilian pediatric myelodysplastic cooperative group strategies: are they relevant to improve educational approach and correct diagnosis?","volume":"26","author":"Lopes","year":"2002","journal-title":"Leuk Res"},{"key":"10.1002\/pbc.26285-BIB0024|pbc26285-cit-0024","first-page":"418292","article-title":"5-Azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity","author":"St\u00fcbig","year":"2014","journal-title":"Mediators Inflamm"},{"key":"10.1002\/pbc.26285-BIB0025|pbc26285-cit-0025","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.3324\/haematol.2011.048421","article-title":"Multicenter validation of a reproducible flow cytometric score for the diagnosis of low-grade myelodysplastic syndromes: results of a European LeukemiaNET study","volume":"97","author":"Della Porta","year":"2012","journal-title":"Haematologica"},{"key":"10.1002\/pbc.26285-BIB0026|pbc26285-cit-0026","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1182\/blood-2015-09-669937","article-title":"Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents","volume":"127","author":"Wlodarski","year":"2016","journal-title":"Blood"},{"key":"10.1002\/pbc.26285-BIB0027|pbc26285-cit-0027","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1038\/ng.913","article-title":"Heritable GATA2 mutations associates with familial myelodysplastic syndrome and acute myeloid leukemia","volume":"43","author":"Hahn","year":"2011","journal-title":"Nat Genet"},{"key":"10.1002\/pbc.26285-BIB0028|pbc26285-cit-0028","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1111\/bjh.13317","article-title":"Hematopoietic and immune defects associated with GATA2 mutation","volume":"169","author":"Collin","year":"2015","journal-title":"Brit J Hemtol"}],"container-title":["Pediatric Blood & Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.26285","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.26285","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/pbc.26285\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T13:54:32Z","timestamp":1657461272000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.26285"}},"subtitle":["Oliveira et\u00a0al."],"short-title":[],"issued":{"date-parts":[[2016,10,17]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"URL":"https:\/\/doi.org\/10.1002\/pbc.26285","archive":["Portico"],"relation":{},"ISSN":["1545-5009"],"issn-type":[{"value":"1545-5009","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10,17]]}}}