{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T07:47:58Z","timestamp":1784620078775,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T00:00:00Z","timestamp":1493942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Copper deficiency is a known cause of anemia and neutropenia that is easily remedied with copper supplementation. Copper is primarily absorbed in the stomach and proximal duodenum, so patients receiving enteral nutrition via methods that bypass this critical region may be at increased risk for copper deficiency. In pediatrics, postpyloric enteral feeding is increasingly utilized to overcome problems related to aspiration, severe reflux, poor gastric motility, and gastric outlet obstruction. However, little is known about the prevalence of copper deficiency in this population. We describe three pediatric patients receiving exclusive jejunal feeds who developed cytopenias secondary to copper deficiency.<\/jats:p>","DOI":"10.1002\/pbc.26617","type":"journal-article","created":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T14:23:02Z","timestamp":1493994182000},"source":"Crossref","is-referenced-by-count":14,"title":["Refractory cytopenias secondary to copper deficiency in children receiving exclusive jejunal nutrition"],"prefix":"10.1002","volume":"64","author":[{"given":"Amanda E.","family":"Jacobson","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology\/BMT Nationwide Children's Hospital  Columbus Ohio"},{"name":"Department of Pediatrics Ohio State University College of Medicine  Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir B.","family":"Kahwash","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Nationwide Children's Hospital  Columbus Ohio"},{"name":"Department of Pathology Ohio State University College of Medicine  Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjulika","family":"Chawla","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology Hasbro Children's Hospital  Providence Rhode Island"},{"name":"Department of Pediatrics The Warren Alpert Medical School of Brown University  Providence Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,5,5]]},"reference":[{"issue":"2","key":"e_1_2_6_2_1","first-page":"132","article-title":"Copper in parenteral nutrition","volume":"60","author":"Shike M.","year":"1984","journal-title":"Bull NY Acad Med"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2008.01050.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g3691"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-016-2162-8"},{"issue":"2","key":"e_1_2_6_6_1","first-page":"118","article-title":"Copper deficiency in humans","volume":"20","author":"Williams DM.","year":"1983","journal-title":"Semin Hematol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-198807000-00018"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2011.04.008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000431186"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2009.06.009"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607106030005446"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1258\/0004563053857879"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0261-5614(97)80239-7"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5511-x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/67.5.1054S"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607194018002185"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004563215620821"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1309\/V6GVYW2QTYD5C5PJ"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.26617","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.26617","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T03:37:23Z","timestamp":1696477043000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.26617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,5]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1002\/pbc.26617"],"URL":"https:\/\/doi.org\/10.1002\/pbc.26617","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,5]]},"article-number":"e26617"}}