{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:51:23Z","timestamp":1786978283218,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T00:00:00Z","timestamp":1505779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Opsoclonus myoclonus ataxia syndrome (OMAS) can be refractory to standard therapies and devastating. Alternative treatments are imperative. A 14\u2010month\u2010old male diagnosed with neuroblastoma and paraneoplastic OMAS achieved complete cancer remission with chemotherapy. The OMAS, however, persisted over the subsequent 4 years despite numerous immune\u2010modulatory and immunosuppressive therapies. The patient ultimately achieved complete remission following therapeutic plasma exchange (TPE) combined with rituximab and intravenous immunoglobulin. After three asymptomatic years, he relapsed. Upon reintroducing TPE and rituximab plus oral prednisolone, the patient rapidly achieved a second complete remission. This case offers proof\u2010of\u2010principle for the potential efficacy of TPE for neuroblastoma\u2010associated OMAS.<\/jats:p>","DOI":"10.1002\/pbc.26819","type":"journal-article","created":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T12:26:38Z","timestamp":1505823998000},"source":"Crossref","is-referenced-by-count":8,"title":["Therapeutic plasma exchange for a case of refractory opsoclonus myoclonus ataxia syndrome"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7844-4558","authenticated-orcid":false,"given":"Jocelyn E.","family":"Greensher","sequence":"first","affiliation":[{"name":"Hofstra Northwell School of Medicine Hempstead New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Louie","sequence":"additional","affiliation":[{"name":"Hofstra Northwell School of Medicine Hempstead New York"},{"name":"Department of Pathology, Transfusion Medicine Long Island Jewish Medical Center New Hyde Park New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D.","family":"Fish","sequence":"additional","affiliation":[{"name":"Hofstra Northwell School of Medicine Hempstead New York"},{"name":"Division of Pediatric Hematology\/Oncology and Stem Cell Transplantation Steven and Alexandra Cohen Children's Medical Center New Hyde Park New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24659"},{"issue":"1","key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1542\/peds.109.1.86","article-title":"Opsoclonus\u2010ataxia caused by childhood neuroblastoma: developmental and neurological sequelae","volume":"109","author":"Mitchell WG","year":"2002","journal-title":"Pediatrics"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21009"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32833fde3f"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.204792"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-3114"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073814549581"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10283"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2377"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-015-0401-7"},{"issue":"3","key":"e_1_2_6_12_1","first-page":"120","article-title":"Therapeutic plasma exchange: applications in neurology","volume":"60","author":"Lainez\u2010Andres JM","year":"2015","journal-title":"Rev Neurol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21331"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1237723"},{"issue":"6","key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.33588\/rn.6206.2015428","article-title":"Neuropsychological profile in opsoclonus\u2010myoclonus\u2010ataxia syndrome presenting as neuroblastic tumors","volume":"62","author":"Bravo J","year":"2016","journal-title":"Rev Neurol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2015.11.007"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2005.05.018"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(00)00227-7"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.26819","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.26819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T16:26:53Z","timestamp":1750868813000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.26819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,19]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1002\/pbc.26819"],"URL":"https:\/\/doi.org\/10.1002\/pbc.26819","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,19]]},"article-number":"e26819"}}