{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T23:16:09Z","timestamp":1789859769360,"version":"4.0.1"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,10,8]],"date-time":"2017-10-08T00:00:00Z","timestamp":1507420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Larry and Helen Hoag Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study sought to characterize cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>In this cross\u2010sectional cohort study, Latino survivors of ALL (n\u00a0=\u00a057) and LL (n\u00a0=\u00a05) aged 6\u201316 years were pooled and evaluated using validated measures of cognitive, academic, and behavioral function and English language proficiency. Performance was compared with norms using single\u2010sample <jats:italic>t<\/jats:italic>\u2010tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this cohort (<jats:italic>n\u00a0<\/jats:italic>=\u00a062, 50% male), mean ages at diagnosis and testing were 4.5 and 10.8 years, respectively; mean time off treatment was 44.7 months. All participants spoke English and over half (57%) identified Spanish as the primary language in the home. Forty\u2010two families (68%) placed in the two lowest Hollingshead socioeconomic status categories. Participants were below average for working memory (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Overall, participants were in the average range, but significantly lower than published norms on domain\u2010specific measures of verbal comprehension (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); perceptual reasoning (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.033); processing speed (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.003); visual memory (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); visuomotor attention, scanning, and sequencing (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005); and reading comprehension (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001). Parents reported concerns with working memory (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and metacognition (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.014).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Similar to other childhood ALL\/LL survivors, overall cognitive function in this Latino sample was relatively preserved but selected deficits were observed. Routine cognitive screening is indicated in this population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.26844","type":"journal-article","created":{"date-parts":[[2017,10,8]],"date-time":"2017-10-08T11:52:46Z","timestamp":1507463566000},"source":"Crossref","is-referenced-by-count":17,"title":["Cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia and lymphoma: A cross\u2010sectional cohort study using culturally competent, performance\u2010based assessment"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6183-2423","authenticated-orcid":false,"given":"Laura","family":"Bava","sequence":"first","affiliation":[{"name":"Survivorship and Supportive Care Program Children's Center for Cancer and Blood Diseases Children's Hospital Los Angeles  Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Johns","sequence":"additional","affiliation":[{"name":"Department of Plastic and Maxillofacial Surgery Keck School of Medicine University of Southern California  Los Angeles California"},{"name":"Department of Pediatrics Keck School of Medicine University of Southern California  Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Kayser","sequence":"additional","affiliation":[{"name":"Survivorship and Supportive Care Program Children's Center for Cancer and Blood Diseases Children's Hospital Los Angeles  Los Angeles California"},{"name":"Department of Pediatrics Keck School of Medicine University of Southern California  Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5280-990X","authenticated-orcid":false,"given":"David R.","family":"Freyer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Keck School of Medicine University of Southern California  Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,8]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"SEER Cancer Statistics Review, 1975-2013","author":"Howlader N","year":"2016"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/08880018.2013.789574"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14035"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/arclin\/15.7.603"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2015.03.016"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20860"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-007-0369-x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-02-627414"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.26117"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-7584-3_15"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs344"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.64.3205"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25690"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(16)30283-8"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.48.2315"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2008.11.003"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2897"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0165025415603489"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-71758-6_4"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24608"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4188"},{"key":"e_1_2_7_23_1","unstructured":"United States Census Bureau.American FactFinder Community Facts.2017.http:\/\/factfinder.census.gov\/faces\/nav\/jsf\/pages\/community_facts.xhtml."},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/10791102009002005"},{"key":"e_1_2_7_25_1","unstructured":"Children's Oncology Group.Long\u2010term follow\u2010up guidelines for survivors of childhood adolescent and young adult cancers.2017.http:\/\/www.survivorshipguidelines.org\/."},{"key":"e_1_2_7_26_1","unstructured":"Children's Oncology Group Study ALTE07C1: Neuropsychological and behavioral testing in younger patients with cancer. 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