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We report the case of a 6\u2010month\u2010old female child with IP who presented with unilateral nystagmus and was found to have a pilocytic astrocytoma with leptomeningeal spread. Enhanced understanding of the relationship between NF\u2010\u0138B, along with its upstream regulators, and tumorigenesis may shed light on whether a subset of patients with IP may be at increased risk for neoplasia.<\/jats:p>","DOI":"10.1002\/pbc.26886","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T08:46:44Z","timestamp":1511513204000},"source":"Crossref","is-referenced-by-count":3,"title":["Pilocytic astrocytoma with leptomeningeal spread in a patient with incontinentia pigmenti presenting with unilateral nystagmus"],"prefix":"10.1002","volume":"65","author":[{"given":"Cheryl B.","family":"Bayart","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Pediatrics Seattle Children's Hospital University of Washington School of Medicine  Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisele E.","family":"Ishak","sequence":"additional","affiliation":[{"name":"Department of Radiology 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