{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:43:53Z","timestamp":1790419433601,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,2,22]],"date-time":"2018-02-22T00:00:00Z","timestamp":1519257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Gerbich (Ge) antigens are high frequency red cell antigens expressed on glycophorin C (GYPC) and glycophorin D. Hemolytic disease of the fetus and newborn (HDFN) due to Gerbich antibody is rare and presents a clinical challenge, as Gerbich negative blood is scarce. We report a case of HDFN due to maternal Ge3 negative phenotype and anti\u2010Ge3 alloimmunization, successfully managed by transfusion of maternal blood. Molecular testing revealed that the mother has homozygous deletion of exon 3 of <jats:italic>GYPC<\/jats:italic>, the father is homozygous wildtype for <jats:italic>GYPC<\/jats:italic>, and the infant is obligate heterozygote expressing Ge3.<\/jats:p>","DOI":"10.1002\/pbc.27014","type":"journal-article","created":{"date-parts":[[2018,2,22]],"date-time":"2018-02-22T12:28:48Z","timestamp":1519302528000},"source":"Crossref","is-referenced-by-count":6,"title":["Molecular characterization and multidisciplinary management of Gerbich hemolytic disease of the newborn"],"prefix":"10.1002","volume":"65","author":[{"given":"Rebecca N.","family":"Levitt","sequence":"first","affiliation":[{"name":"Department of Pediatrics Inova Children's Hospital  Falls Church Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Gourri","sequence":"additional","affiliation":[{"name":"Blood Transfusion Service Zurich Swiss Red Cross (SRC)  Z\u00fcrich\u2010Schlieren Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Gassner","sequence":"additional","affiliation":[{"name":"Blood Transfusion Service Zurich Swiss Red Cross (SRC)  Z\u00fcrich\u2010Schlieren Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Banez\u2010Sese","sequence":"additional","affiliation":[{"name":"Inova Schar Cancer Institute Apheresis Service, Inova Blood Donor Services Inova Donor Services  Sterling Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdus","family":"Salam","sequence":"additional","affiliation":[{"name":"Blood Bank and Transfusion Service Inova Fairfax Hospital  Falls Church Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A.","family":"Denomme","sequence":"additional","affiliation":[{"name":"Diagnostic laboratories BloodCenter of Wisconsin  Milwaukee Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7711-9371","authenticated-orcid":false,"given":"Elizabeth","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Hematology\u2010Oncology Pediatric Specialists of Virginia  Falls Church Virginia"},{"name":"Department of Pediatrics George Washington University School of Medicine  Washington District of Columbia"},{"name":"Virginia Commonwealth University School of Medicine\u2014Inova Campus  Falls Church Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2016.05.008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-204"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14578"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0958-7578.2005.00562.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2005.05407.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06073.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1085072"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12028"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1975.tb00479.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12027"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2004.04082.x"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.27014","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.27014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T08:13:48Z","timestamp":1695543228000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.27014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,22]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1002\/pbc.27014"],"URL":"https:\/\/doi.org\/10.1002\/pbc.27014","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,22]]},"article-number":"e27014"}}