{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T21:38:08Z","timestamp":1764020288831,"version":"3.41.2"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T00:00:00Z","timestamp":1552003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Preoperative diagnosis for tumors arising in the optic chiasm\/sellar\/suprasellar region in children is helpful to determine surgical necessity and approach, given the high operative risk in this area. We evaluated the ability to differentiate tumor type by preoperative neuroimaging. Thirty\u2010eight of 53 tumors were correctly diagnosed by neuroimaging based on final pathologic diagnosis (prediction accuracy 72%). Prediction accuracies were 87% (20\/23) for craniopharyngioma, 79% (11\/14) for optic pathway glioma, 64% (7\/11) for germ cell tumor, and 0% (0\/5) for Langerhans cell histiocytosis. Diagnosis of optic chiasm\/sellar\/suprasellar tumors in children by imaging alone should be considered when biopsy is considered high risk.<\/jats:p>","DOI":"10.1002\/pbc.27680","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T10:18:23Z","timestamp":1552040303000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Diagnostic accuracy of neuroimaging in pediatric optic chiasm\/sellar\/suprasellar tumors"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8317-8952","authenticated-orcid":false,"given":"Gregory A.","family":"Norris","sequence":"first","affiliation":[{"name":"Department of Pediatrics Children's Hospital Colorado University of Colorado School of Medicine  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacquelyn","family":"Garcia","sequence":"additional","affiliation":[{"name":"Division of Pediatric Radiology Children's Hospital Colorado University of Colorado School of Medicine  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd C.","family":"Hankinson","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery Children's Hospital Colorado University of Colorado School of Medicine  Aurora Colorado"},{"name":"Morgan Adams Foundation Pediatric Brain Tumor Research Foundation  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Handler","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery Children's Hospital Colorado University of Colorado School of Medicine  Aurora Colorado"},{"name":"Morgan Adams Foundation Pediatric Brain Tumor Research Foundation  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Foreman","sequence":"additional","affiliation":[{"name":"Morgan Adams Foundation Pediatric Brain 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