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Bevacizumab is a documented treatment for progressive LGG, yet the impact of therapy on the cystic component of these tumors is unknown. We present four patients with prominently cystic LGG treated with bevacizumab at the time of progression. In each case, the cystic component responded to treatment. This is the first known study to investigate bevacizumab's impact on the cystic component of low\u2010grade gliomas.<\/jats:p>","DOI":"10.1002\/pbc.27917","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T11:00:08Z","timestamp":1564138808000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Bevacizumab in treating the cystic components of pediatric low\u2010grade gliomas: A report of four patients"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3332-3709","authenticated-orcid":false,"given":"Erica","family":"Levenbaum","sequence":"first","affiliation":[{"name":"The University of Rochester School of Medicine and Dentistry  Rochester New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shehanaz","family":"Ellika","sequence":"additional","affiliation":[{"name":"Department of Imaging The University of Rochester Medical Center  Rochester New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David N.","family":"Korones","sequence":"additional","affiliation":[{"name":"The University of Rochester School of Medicine and Dentistry  Rochester New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2010.02.003"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/nou223"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.73.0242"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1997.15.8.2792"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01705-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000000371"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/not154"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24297"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21935"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1799"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27234"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(97)00218-8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568011033353452"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1985.62.6.0811"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.57.12.1497"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvq105"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/978-3-7091-1434-6_34","article-title":"Decrease in the apparent diffusion coefficient in peritumoral edema for the assessment of recurrent glioblastoma treated by bevacizumab","volume":"118","author":"Takano S","year":"2013","journal-title":"Acta Neurochir Suppl"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.10.5825"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyw101"}],"container-title":["Pediatric Blood &amp; 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