{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:40:47Z","timestamp":1790109647871,"version":"4.0.1"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Sclerotherapy or surgical resection is options for symptomatic venous malformations (VM). Sclerotherapy may require repetitive intervention and resection is often avoided due to operative morbidity. The purpose of this study was to report use of single\u2010stage n\u2010butyl cyanoacrylate glue embolization and surgical resection of focal VM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A review of patients with focal VM who underwent glue embolization followed by resection at a single tertiary care vascular malformations center was performed. All embolizations were performed with ultrasound and fluoroscopy under the same anesthetic as resection. Patient characteristics and outcomes were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifteen procedures were performed in 12 patients with a total of 20 VM addressed, as several patients had multiple VM. Mean age was 16 \u00b1 9 years. Malformation locations included scalp, hip, gluteal, labial, toe, finger, face, lip, chest, and foot and size ranged from 1.0 to 10.5\u00a0cm. Median (range) of prior sclerotherapy treatments was 3 (0\u20105) and three patients previously underwent surgical resection. Median blood loss was zero (0\u201010) mL. Surgical complications occurred after five procedures (33%) including superficial wound dehiscence and cellulitis. No complications required readmission or reoperation. At a median follow up of 195 (103\u2010266) days, no patients have required additional treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Glue embolization and resection of focal VM of variable size and location appears to have durable results and low surgical morbidity. This single\u2010stage procedure, often performed as an outpatient, may be utilized as upfront treatment for symptomatic malformations or for VM refractory to other treatments.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.28029","type":"journal-article","created":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T05:26:07Z","timestamp":1574313967000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Single\u2010stage embolization with n\u2010butyl cyanoacrylate and surgical resection of venous malformations"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1947-5439","authenticated-orcid":false,"given":"Stephanie F.","family":"Polites","sequence":"first","affiliation":[{"name":"Division of General and Thoracic Surgery Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of General and Thoracic Surgery Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Scorletti","sequence":"additional","affiliation":[{"name":"Division of General and Thoracic Surgery Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish N.","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Interventional Radiology Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7253-5632","authenticated-orcid":false,"given":"Kiersten W.","family":"Ricci","sequence":"additional","affiliation":[{"name":"Division of Hematology, Cancer and Blood Diseases Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0820-4924","authenticated-orcid":false,"given":"Adrienne M.","family":"Hammill","sequence":"additional","affiliation":[{"name":"Division of Hematology, Cancer and Blood Diseases Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4839-4937","authenticated-orcid":false,"given":"Roshni","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Division of General and Thoracic Surgery Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.21037\/cdt.2016.11.10"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2014.06.019"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199907000-00002"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0268355513477282"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813475586"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198602203140804"},{"issue":"4","key":"e_1_2_8_8_1","first-page":"777","article-title":"n\u2010Butyl 2\u2010cyanoacrylate\u2013substitute for IBCA in interventional neuroradiology: histopathologic and polymerization time studies","volume":"10","author":"Brothers MF","year":"1989","journal-title":"AJNR Am J Neuroradiol"},{"issue":"5","key":"e_1_2_8_9_1","first-page":"748","article-title":"N\u2010butyl cyanoacrylate embolization of cerebral arteriovenous malformations: results of a prospective, randomized, multi\u2010center trial","volume":"23","author":"n\u2010BCA Trail Investigators","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1538574418762192"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/66893325"},{"key":"e_1_2_8_12_1","unstructured":"Federal Drug Administration. 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