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Conventional chemotherapy is poorly tolerated by patients with AT, with excessive toxicity even when doses are reduced. Here, we report on two patients with AT and EBV\u2010positive neoplasms who were treated with EBV\u2010targeted viral\u2010specific T cells (VST). One patient had a prolonged complete response to VSTs while the other had a partial response. Therapy was well tolerated without infusion toxicity or graft\u2010versus\u2010host disease.<\/jats:p>","DOI":"10.1002\/pbc.28126","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T12:38:29Z","timestamp":1576672709000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["EBV\u2010directed viral\u2010specific T\u2010lymphocyte therapy for the treatment of EBV\u2010driven lymphoma in two patients with primary immunodeficiency and DNA repair defects"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1934-2954","authenticated-orcid":false,"given":"Jeremy D.","family":"Rubinstein","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio"},{"name":"Division of Bone Marrow Transplantation and Immune Deficiency Cancer and Blood Disease Institute Cincinnati Children's Hospital Medical 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