{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:06:06Z","timestamp":1790316366162,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T00:00:00Z","timestamp":1591228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Irving Institute for Clinical and Translational Research at Columbia University Irving Medical Center"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Survival disparities by race\/ethnicity and socioeconomic status (SES) are observed in a wide range of pediatric treatment settings including oncology and solid organ transplantation. To date, few studies have examined the effects of race and SES on outcomes in pediatric allogeneic hematopoietic cell transplantation (HCT). We explored whether survival differed by race\/ethnicity or SES in children receiving HCT for nonmalignant conditions at a single institution serving a diverse patient population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>The Kaplan\u2010Meier method was used to estimate overall survival (OS) with the log\u2010rank test for between\u2010group comparisons. Cox proportional hazards models were used to identify risk factors for OS, adjusting for treatment\u2010 and disease\u2010related factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 133 subjects, 0 to 21 years, 19% were non\u2010Hispanic (NH) white, 34% were NH black, 40% were Hispanic, and 7% were Asian. Sixty\u2010seven percent of the subjects had public insurance; 49% lived in neighborhoods with poverty rate \u226520%. Primary diagnoses included hemoglobinopathies (56%), bone marrow failure (22%), and other conditions (22%). Median follow\u2010up was 5.8 years (range 0.1\u201014.5). Analysis revealed no difference in OS by race, insurance type, or neighborhood SES.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Findings from this single\u2010institution study suggest that in pediatric patients undergoing HCT for nonmalignant conditions, treatment at a tertiary care center with a multidisciplinary approach may mitigate drivers of disparities observed in other settings. Additional studies are now needed to further elucidate the complex interrelationships among race, SES, and clinical outcomes for children undergoing HCT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.28367","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T16:50:25Z","timestamp":1591289425000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Race and socioeconomic status in pediatric allogeneic hematopoietic cell transplantation for nonmalignant conditions"],"prefix":"10.1002","volume":"67","author":[{"given":"Sarah M.","family":"Harney","sequence":"first","affiliation":[{"name":"Department of Pediatrics Hasbro Children's Hospital, Brown University  Providence Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3330-6754","authenticated-orcid":false,"given":"Justine M.","family":"Kahn","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation Department of Pediatrics Columbia University Medical Center  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhezhen","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Mailman School of Public Health Columbia University  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscilla","family":"Wong","sequence":"additional","affiliation":[{"name":"Compliance Department New York City Housing Authority  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"McKetta","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Mailman School of Public Health Columbia University  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Satwani","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation Department of Pediatrics Columbia University Medical Center  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-3109"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23769"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2437"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03241.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2014.10.016"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05337.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2017.08.034"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/15265161.2019.1665736"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2012.12.005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-018-0308-0"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197410000-00001"},{"key":"e_1_2_9_13_1","unstructured":"U.S.C. Bureau.Race;2018.https:\/\/www.census.gov\/topics\/population\/race\/about.html. Accessed December 1 2019."},{"issue":"1","key":"e_1_2_9_14_1","first-page":"607","article-title":"Survival by race\/ethnicity in children and adolescents with Hodgkin lymphoma treated on cooperative group trials in the U.S. and Canada: a pooled analysis of Children's Oncology Group trials","volume":"130","author":"Kahn JM","year":"2017","journal-title":"Blood"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj313"},{"key":"e_1_2_9_16_1","unstructured":"Federal Financial Institutions Examination Council.FFIEC Geocoding\/Mapping System;2019.https:\/\/geomap.ffiec.gov\/FFIECGeocMap\/GeocodeMap1.aspx?. Accessed March 1 2020."},{"key":"e_1_2_9_17_1","unstructured":"Federal Financial Institutions Examination Council.FFIEC Online Census Data System;2019.https:\/\/www.ffiec.gov\/census\/default.aspx. Accessed March 1 2020."},{"key":"e_1_2_9_18_1","unstructured":"Bureau of the Census.Poverty Areas.U.S.\u00a0Department\u00a0of Commerce;1995.https:\/\/www.census.gov\/population\/socdemo\/statbriefs\/povarea.html. Accessed March 1 2020."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.03.133"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2004.12.327"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.07.023"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.44"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2014.941834"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.166"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2016.08.016"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2017.10.009"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.20.2709"},{"key":"e_1_2_9_28_1","unstructured":"PolubriaginofF Andrea Wells ShapiroHS PreyJ et\u00a0al.Patient\u2010provided data improves race and ethnicity data quality in electronic health records. American Medical Informatics Association Annual Symposium Chicago IL;2016."},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.22.2879"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(02)00073-4"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwf068"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.12.536"},{"key":"e_1_2_9_33_1","first-page":"25","article-title":"Projections of the size and composition of the U.S. Population: 2014 to 2060","author":"Colby SL","year":"2015","journal-title":"Curr Popul Rep"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.246"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174760"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25297"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60237-3"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.28367","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.28367","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pbc.28367","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.28367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T05:45:06Z","timestamp":1693892706000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.28367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,4]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1002\/pbc.28367"],"URL":"https:\/\/doi.org\/10.1002\/pbc.28367","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,4]]},"assertion":[{"value":"2020-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e28367"}}