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We report on a young man with primary mediastinal B\u2010cell lymphoma invading into the trachea, requiring a 40\u2010day ECMO run who underwent fluorodeoxyglucose positron emission tomography (FDG\u2010PET) imaging and treatment with concurrent mediastinal irradiation and continuous infusion chemotherapy while on this life\u2010saving technology. This case illustrates that oncology patients may be managed by multidisciplinary teams for extended periods in extraordinary circumstances using multimodality therapies. Additionally, to our knowledge this is the first case to demonstrate the feasibility of FDG\u2010PET imaging while on ECMO.<\/jats:p>","DOI":"10.1002\/pbc.28429","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T12:29:21Z","timestamp":1594902561000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Continuous infusion chemotherapy, radiotherapy, and FDG\u2010PET are feasible during extracorporeal membrane oxygenation"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2896-1113","authenticated-orcid":false,"given":"Seth J.","family":"Rotz","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology Oncology, and Blood and Marrow Transplantation Cleveland Clinic Children's Hospital  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco 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