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We therefore collected and analyzed the published data on symptomatic infection from cytomegalovirus, herpes simplex virus, varicella zoster virus, parvovirus B19, or adenovirus in pediatric acute leukemia. Reports on 68 children were identified, of whom 16 patients have died from the infection. Further studies have to (1) evaluate the true incidence of these infections in pediatric acute leukemia, (2) their impact on outcome, and (3) whether a subpopulation of patients could benefit from screening and prophylactic strategies.<\/jats:p>","DOI":"10.1002\/pbc.28673","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T07:09:55Z","timestamp":1600931395000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Systemic viral infection in children receiving chemotherapy for acute leukemia"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6245-8699","authenticated-orcid":false,"given":"Constanze","family":"Buus\u2010Gehrig","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology and Oncology Hospital for Children and Adolescents Johann Wolfgang Goethe\u2010University  Frankfurt 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