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Proton therapy is currently used safely and effectively for many types of both pediatric and adult cancer, and its main advantage is the sparing of healthy tissues from radiation, which could translate in the reduction of late side effects. We review the literature on radiotherapy and proton therapy for pediatric meningiomas and report clinical outcomes for two aggressive pediatric meningiomas we treated with protons. Proton therapy might be a safe and effective therapeutic option for this rare subgroup of tumors.<\/jats:p>","DOI":"10.1002\/pbc.28919","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T06:15:35Z","timestamp":1615184135000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Proton therapy: A therapeutic opportunity for aggressive pediatric meningioma"],"prefix":"10.1002","volume":"68","author":[{"given":"Barbara","family":"Rombi","sequence":"first","affiliation":[{"name":"Proton Therapy Center Santa Chiara Hospital  Trento Italy"},{"name":"Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, DIMES University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Ruggi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Bologna  Bologna 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