{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:41:05Z","timestamp":1791222065702,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Shwachman\u2010Diamond syndrome with Shwachman\u2010Bodian\u2010Diamond syndrome (<jats:italic>SBDS<\/jats:italic>) biallelic variants is a rare disorder that predisposes the carrier to malignant hemopathies but solid\u2010cancer predisposition is poorly known. Among 155 cases entered in the French Registry for Severe Chronic Neutropenia, three were identified with malignant solid tumors (ovary, breast, and esophagus). All cancers occurred during the fifth decade and, despite being localized at diagnosis, were rapidly fatal thereafter. No cancer was observed post transplantation in the 14 HSCT survivors. Based on the literature and our patient data, we can merely advance that this complication is predominantly diagnosed in adults.<\/jats:p>","DOI":"10.1002\/pbc.29071","type":"journal-article","created":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T22:25:17Z","timestamp":1618871117000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Shwachman\u2010Diamond syndrome and solid tumors: Three new patients from the French Registry for Severe Chronic Neutropenia and literature review"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2773-048X","authenticated-orcid":false,"given":"Fares","family":"Bou Mitri","sequence":"first","affiliation":[{"name":"Centre de Recherche Saint\u2010Antoine, APHP, Armand\u2010Trousseau Hospital, French Registry for Severe Chronic Neutropenia, CRMR of Chronic Neutropenia, Department of Pediatrics Hematology and Oncology Sorbonne Universit\u00e9, Inserm  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandine","family":"Beaupain","sequence":"additional","affiliation":[{"name":"Centre de Recherche Saint\u2010Antoine, APHP, Armand\u2010Trousseau Hospital, French Registry for Severe Chronic Neutropenia, CRMR of Chronic Neutropenia, Department of Pediatrics Hematology and Oncology Sorbonne Universit\u00e9, Inserm  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Flejou","sequence":"additional","affiliation":[{"name":"Department of Pathology Saint\u2010Antoine Hospital, APHP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Patient","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology H\u00f4pital d'Instruction des Arm\u00e9es (HIA) Sainte\u2010Anne  Toulon 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