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She received adjuvant ifosfamide and doxorubicin, followed by concurrent proton radiotherapy and ifosfamide. Radiotherapy included 66\u00a0Gy (RBE) in 33 fractions to the operative bed. Prospectively graded toxicities included Grade 2 esophagitis and Grade 1 anorexia, dermatitis, and fatigue. She completed six cycles of ifosfamide. Two years post operation, she had no evidence of disease, intermittent palpitations with normal cardiac function, and no other cardiopulmonary or esophageal symptoms.<\/jats:p>","DOI":"10.1002\/pbc.29241","type":"journal-article","created":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T13:27:31Z","timestamp":1626269251000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Adjuvant chemoradiation for high\u2010grade cardiac leiomyosarcoma in a child: Case report and review of literature"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3612-4852","authenticated-orcid":false,"given":"James","family":"Janopaul\u2010Naylor","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Winship Cancer Institute at Emory University  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirk R.","family":"Kanter","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac Surgery, Department of Surgery Emory University School of Medicine  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stella","family":"Flampouri","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Winship Cancer Institute at Emory University  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivi","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Winship Cancer Institute at Emory University  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6691-5380","authenticated-orcid":false,"given":"Thomas A.","family":"Olson","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology Children's Healthcare of Atlanta  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2431-2933","authenticated-orcid":false,"given":"Bree R.","family":"Eaton","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Winship Cancer Institute at Emory University  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000000059"},{"key":"e_1_2_6_3_1","unstructured":"A Review of Malignant Primary Cardiac Tumors \u2010 American College of Cardiology.https:\/\/www.acc.org\/latest\u2010in\u2010cardiology\/articles\/2018\/04\/20\/08\/41\/a\u2010review\u2010of\u2010malignant\u2010primary\u2010cardiac\u2010tumors. 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