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Kaposiform hemangioendothelioma (KHE) may be complicated with Kasabach\u2013Merritt phenomenon (KMP) and stagnant blood flow in slow\u2010flow malformations can promote activation and consumption of coagulation factors, which results in bleeding and clotting known as localized intravascular coagulopathy (LIC). These patients can experience significant morbidity secondary to pain due to thrombosis and are at higher risk of hematologic complications during surgical procedures. No standard of care has been established to prevent or manage these complications. This review focuses on the management of coagulopathy in children and adults with vascular anomalies.<\/jats:p>","DOI":"10.1002\/pbc.29353","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T16:46:01Z","timestamp":1662569161000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["How we approach coagulopathy with vascular anomalies"],"prefix":"10.1002","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3893-4709","authenticated-orcid":false,"given":"Joana M.","family":"Mack","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Hematology\/Oncology University of Arkansas for Medical Sciences  Little Rock Arkansas USA"},{"name":"Arkansas Children's Hospital  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5133-9624","authenticated-orcid":false,"given":"Shelley 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