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The recommendations are based on two systematic reviews of randomized controlled trials evaluating interventions to prevent (1) acute phase CINV and (2) delayed phase CINV. Recommendations for acute phase and delayed phase CINV prophylaxis are made for patients receiving chemotherapy of varying emetogenicity, as well as for patients not able to receive dexamethasone or a neurokinin\u20101 receptor antagonist. Evidence gaps, including antiemetic safety and optimal dosing, were identified.<\/jats:p>","DOI":"10.1002\/pbc.30001","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T02:37:44Z","timestamp":1665542264000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Prevention of acute and delayed chemotherapy\u2010induced nausea and vomiting in pediatric cancer patients: A clinical practice guideline"],"prefix":"10.1002","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2872-5412","authenticated-orcid":false,"given":"Priya","family":"Patel","sequence":"first","affiliation":[{"name":"Pediatric Oncology Group of Ontario  Toronto Canada"},{"name":"Department of Pharmacy The Hospital for Sick Children  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula D.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Pediatric Oncology Group of Ontario  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Cohen","sequence":"additional","affiliation":[{"name":"Not applicable (patient representative)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1003-8905","authenticated-orcid":false,"given":"Katie","family":"Devine","sequence":"additional","affiliation":[{"name":"Rutgers Cancer Institute of New Jersey  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Gibson","sequence":"additional","affiliation":[{"name":"Pediatric Oncology Group of Ontario  Toronto Canada"},{"name":"Division of Haematology\/Oncology McMaster Children's Hospital  Hamilton Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark T.","family":"Holdsworth","sequence":"additional","affiliation":[{"name":"College of Pharmacy University of New Mexico  Albuquerque New Mexico USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloise","family":"Neumann","sequence":"additional","affiliation":[{"name":"Birmingham Women's and Children's Hospital  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Orsey","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology Connecticut Children's Medical Center  Hartford Connecticut USA"},{"name":"Department of Pediatrics University of Connecticut School of Medicine  Farmington Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Haematology and Oncology Leeds Teaching Hospital NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Spinelli","sequence":"additional","affiliation":[{"name":"Not applicable (patient representative)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1135-5723","authenticated-orcid":false,"given":"Jennifer","family":"Thackray","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"van de Wetering","sequence":"additional","affiliation":[{"name":"Princess Maxima Center for Pediatric Oncology  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Woods","sequence":"additional","affiliation":[{"name":"University of California Davis Health Pediatric Hematology\/Oncology  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Cabral","sequence":"additional","affiliation":[{"name":"Pediatric Oncology Group of Ontario  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Division of Haematology\/Oncology The Hospital for Sick Children  Toronto Canada"},{"name":"Child Health Evaluative Sciences Research Institute The Hospital for Sick Children  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7699-1061","authenticated-orcid":false,"given":"L. 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