{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:00:36Z","timestamp":1780920036550,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Autoimmune myelofibrosis (AIMF) is a rare disorder characterized by cytopenias and autoimmunity, with characteristic bone marrow findings that include lymphocytic infiltration and fibrosis. AIMF is described predominantly in adult populations who have systemic lupus erythematosis (SLE), with scant pediatric cases described mainly in older adolescents with SLE. Here, we described the largest single\u2010center pediatric experience of pediatric autoimmune myelofibrosis (PAIMF) series, demonstrating both similarities and distinctions from the adult experience. Patients overall respond well to steroid therapy, but these patients were significantly younger, infrequently carried a diagnosis of SLE, and causative genetic lesions were identified in many cases.<\/jats:p>","DOI":"10.1002\/pbc.30144","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T12:14:41Z","timestamp":1674216881000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pediatric autoimmune myelofibrosis: Experience from a large pediatric tertiary care center"],"prefix":"10.1002","volume":"70","author":[{"given":"Taylor Olmsted","family":"Kim","sequence":"first","affiliation":[{"name":"Texas Children's Cancer and Hematology Center  Houston Texas USA"},{"name":"Departments of Pediatrics and Pathology &amp; Immunology Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choladda V.","family":"Curry","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Pathology &amp; Immunology Baylor College of Medicine  Houston Texas USA"},{"name":"Texas Children's Hospital Department of Pathology  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Wiszniewska","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Molecular and Medical Genetics Oregon Health &amp; Science University  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Tarek","family":"Elghetany","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Pathology &amp; Immunology Baylor College of Medicine  Houston Texas USA"},{"name":"Texas Children's Hospital Department of Pathology  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa R. Forbes","family":"Satter","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Pathology &amp; Immunology Baylor College of Medicine  Houston Texas USA"},{"name":"Immunology Allergy and Retrovirology and William T. Shearer Texas Children's Hospital Center for Human Immunobiology  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda B.","family":"Grimes","sequence":"additional","affiliation":[{"name":"Texas Children's Cancer and Hematology Center  Houston Texas USA"},{"name":"Departments of Pediatrics and Pathology &amp; Immunology Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny M.","family":"Despotovic","sequence":"additional","affiliation":[{"name":"Texas Children's Cancer and Hematology Center  Houston Texas USA"},{"name":"Departments of Pediatrics and Pathology &amp; Immunology Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000479103"},{"issue":"9","key":"e_1_2_6_3_1","first-page":"619","article-title":"Distinguishing autoimmune myelofibrosis from primary myelofibrosis","volume":"16","author":"Marcellino B","year":"2018","journal-title":"Clin Adv Hematol Oncol"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12871"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23140"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.28232"},{"issue":"11","key":"e_1_2_6_7_1","first-page":"1207","article-title":"Myelofibrosis secondary to SLE and its reversal on steroid therapy","volume":"32","author":"Agarwal BR","year":"1995","journal-title":"Indian Pediatr"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-3-349"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/rhu.0000000000001533"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.36.11.1219"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000205641"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428190009113399"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-011-1329-6"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-008-0867-y"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199405000-00003"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-693X(96)80007-8"},{"issue":"3","key":"e_1_2_6_17_1","first-page":"255","article-title":"Evans' syndrome, myelofibrosis and systemic lupus erythematosus: role of procollagens in myelofibrosis","volume":"27","author":"Ramakrishna R","year":"1995","journal-title":"Pathology (Phila)"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27439"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.07.020"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.30144","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pbc.30144","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.30144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T17:00:37Z","timestamp":1692637237000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.30144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,20]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/pbc.30144"],"URL":"https:\/\/doi.org\/10.1002\/pbc.30144","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,20]]},"assertion":[{"value":"2022-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e30144"}}