{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:15:14Z","timestamp":1792757714830,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Despite needing to be informed about sickle cell trait (SCT) status to make informed reproductive decisions, more than 80% of adults with SCT, including parents of children with SCT who have a high prevalence of SCT, do not know their status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>This was a prospective study of parents who received SCT telephone education from the state department of health and then completed SCTaware, a videoconference\u2010administered SCT education program. The objectives were to evaluate knowledge after telephone education and explore if SCTaware closes knowledge gaps. Participants completed a demographic survey, a health literacy assessment, and reported their SCT status. They completed the Sickle Cell Trait Knowledge Assessment before receiving SCTaware, immediately after, and at follow\u2010up visits; high knowledge was a score of 75% or higher correct.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SCTaware and the initial surveys were completed by 61 parents; 45 completed the 6\u2010month surveys. Only 43% of participants had high SCT knowledge after telephone education; 92% achieved high knowledge immediately after, and 84% continued with high knowledge at 6\u00a0months. Most parents reported they were aware of their SCT status after telephone education; 12 changed their response after receiving SCTaware.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest that over half of parents have low SCT knowledge following telephone education, and many may be unaware of their status. SCTaware closes knowledge gaps, leads to high sustained knowledge, and is a potentially scalable tool. Future studies should refine SCTaware and determine if parents use their knowledge to inform their children and reproductive decisions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.30384","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T10:52:26Z","timestamp":1682592746000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Closing knowledge gaps among parents of children with sickle cell trait"],"prefix":"10.1002","volume":"70","author":[{"given":"Chase M.","family":"Beeman","sequence":"first","affiliation":[{"name":"Center for Child Health Equity and Outcomes Research, Nationwide Children's Hospital The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ann","family":"Abrams","sequence":"additional","affiliation":[{"name":"Center for Child Health Equity and Outcomes Research, Nationwide Children's Hospital The Ohio State University  Columbus Ohio USA"},{"name":"Primary Care Pediatrics, Department of Pediatrics Nationwide Children's Hospital  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Zajo","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology\/BMT, Department of Pediatrics Nationwide Children's Hospital  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1630-2102","authenticated-orcid":false,"given":"Joseph","family":"Stanek","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology\/BMT, Department of Pediatrics Nationwide Children's Hospital  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Martinez\u2010Mendez","sequence":"additional","affiliation":[{"name":"Center for Child Health Equity and Outcomes Research, Nationwide Children's Hospital The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4730-8139","authenticated-orcid":false,"given":"Susan E.","family":"Creary","sequence":"additional","affiliation":[{"name":"Center for Child Health Equity and Outcomes Research, Nationwide Children's Hospital The Ohio State University  Columbus Ohio USA"},{"name":"Division of Hematology\/Oncology\/BMT, Department of Pediatrics Nationwide Children's Hospital  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"What is sickle cell trait?","author":"Centers for Disease Control, Prevention"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897\u2010012\u20109537\u20103"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0027\u20109684(15)30155\u20103"},{"issue":"5","key":"e_1_2_8_5_1","first-page":"704","article-title":"Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait","volume":"98","author":"Treadwell MJ","year":"2006","journal-title":"J Natl Med Assoc"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2196\/38780"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021\u2010053454"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.327"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/17538068.2022.2026056"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1370\/afm.405"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e31821435f7"},{"issue":"3","key":"e_1_2_8_12_1","first-page":"1","article-title":"Feasibility of a community\u2010based sickle cell trait testing and counseling program","volume":"9","author":"Housten AJ","year":"2016","journal-title":"J Health Dispar Res Pract"},{"key":"e_1_2_8_13_1","volume-title":"AHRQ Health Literacy Universal Precautions Toolkit","year":"2020"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250\u2010200701000\u201000055"},{"key":"e_1_2_8_15_1","unstructured":"SmithA.U.S. smartphone use in 2015.Pew Research Center; Updated April2015. Accessed July 2 2022.https:\/\/www.pewresearch.org\/internet\/2015\/04\/01\/us\u2010smartphone\u2010use\u2010in\u20102015\/"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2009.05.013"},{"key":"e_1_2_8_17_1","unstructured":"National Assessment of Adult Literacy (NAAL).Institute of Education Sciences National Center for Education Statistics. 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