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This study sought to investigate social adjustment and related factors in children living with SCD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 32 children (50% male, mean age\u00a0=\u00a010.32\u00a0years, SD\u00a0=\u00a03.27) were retrospectively collected from a neuropsychology clinic at a tertiary care pediatric hospital. Social adjustment was measured using the <jats:italic>Behavior Assessment System for Children (BASC\u20103)<\/jats:italic> parent\u2010proxy, withdrawal subscale, and the Pediatric Quality of Life Inventory <jats:italic>(PedsQL) Generic Module<\/jats:italic> Social Functioning self\u2010 and parent\u2010proxy subscales. Other measures captured executive functioning (i.e., <jats:italic>Behavior Rating Inventory of Executive Function, Second Edition (BRIEF\u20102) Parent Form<\/jats:italic>) and non\u2010disease\u2010related associations with social adjustment, including number of years in Canada and family functioning (i.e., <jats:italic>PedsQL Family Impact Module)<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixteen percent of patients reported elevated social adjustment difficulties. Multiple linear regression found better family functioning [<jats:italic>B<\/jats:italic>\u00a0=\u00a0.48, <jats:italic>t<\/jats:italic>\u00a0=\u00a02.65, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.016], and higher executive functioning [<jats:italic>B<\/jats:italic>\u00a0=\u00a0\u2212.43, <jats:italic>t<\/jats:italic>\u00a0=\u00a0\u22122.39, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.028] were related to higher scores on the <jats:italic>PedsQL<\/jats:italic> parent\u2010proxy ratings of social adjustment [<jats:italic>F<\/jats:italic>(4,18)\u00a0=\u00a05.88, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.003]. Male sex [<jats:italic>B<\/jats:italic>\u00a0=\u00a0.54, <jats:italic>t<\/jats:italic>\u00a0=\u00a03.08, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.005], and having lived more years in Canada [<jats:italic>B<\/jats:italic>\u00a0=\u00a0.55, <jats:italic>t<\/jats:italic>\u00a0=\u00a02.81, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.009], were related to higher <jats:italic>PedsQL<\/jats:italic> self\u2010reported social adjustment [<jats:italic>F<\/jats:italic>(4,23)\u00a0=\u00a03.75, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.017]. The model examining the <jats:italic>BASC\u20103<\/jats:italic> withdrawal subscale was not statistically significant [<jats:italic>F<\/jats:italic>(4,16)\u00a0=\u00a01.63, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.22].<\/jats:p><\/jats:sec><jats:sec><jats:title>Implications<\/jats:title><jats:p>Social adjustment in children diagnosed with SCD warrants future research to understand the influence of executive function, and non\u2010disease\u2010related factors, particularly focusing on sociocultural factors.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.30807","type":"journal-article","created":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T08:44:38Z","timestamp":1702975478000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Social adjustment in children diagnosed with sickle cell disease: A retrospective study"],"prefix":"10.1002","volume":"71","author":[{"given":"Hailey M.","family":"Zwicker","sequence":"first","affiliation":[{"name":"Hematology, Oncology, Transplant Program Alberta Children's Hospital  Calgary Alberta Canada"},{"name":"Department of Pediatrics Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taryn B.","family":"Fay\u2010McClymont","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Neuropsychology Services Alberta Children's Hospital  Calgary Alberta Canada"},{"name":"Department of Psychology University of British Columbia Okanagan  Kelowna British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5828-6820","authenticated-orcid":false,"given":"Sharon H. 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