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There is great need for noninvasive and easily measured blood laboratory biomarkers that can aid not only in diagnosis, but also management of treatments for vascular anomalies. Angiopoietin\u20102, a circulating blood angiogenic factor, is highly elevated in patients with kaposiform hemangioendothelioma with Kasabach\u2013Merritt phenomenon and kaposiform lymphangiomatosis. Here, we describe our clinical experience using serum angiopoietin\u20102 as a biomarker for diagnosis and monitoring response to treatment.<\/jats:p>","DOI":"10.1002\/pbc.30921","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T04:24:33Z","timestamp":1709612673000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["How we use angiopoietin\u20102 in the diagnosis and management of vascular anomalies"],"prefix":"10.1002","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8604-5511","authenticated-orcid":false,"given":"Elissa R.","family":"Engel","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"},{"name":"Cancer and Blood Diseases Institute Cincinnati Children's Hospital Medical Center  Cincinnati Ohio 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