{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T03:20:09Z","timestamp":1788232809757,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Acute appendicitis (AA) in pediatric patients with acute leukemia mandates prompt treatment. Diagnosis presents challenges, relying on clinical and radiological assessments, often leading to treatment delays that may disrupt leukemia management. Our study on 14 such cases underscores the pivotal role of swift intervention. While conservative AA treatment may pose no risk to healthy children, our findings mandate the performance of laparoscopic appendectomy within 24\u00a0hours of diagnosis. This strategy yielded successful surgical outcomes while ensuring uninterrupted leukemia care. Our experience contributes important insights to the limited understanding of navigating this complex clinical scenario.<\/jats:p>","DOI":"10.1002\/pbc.31114","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T01:23:51Z","timestamp":1717637031000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Management of acute appendicitis in pediatric patients with acute leukemia: Insights from a single\u2010center study"],"prefix":"10.1002","volume":"71","author":[{"given":"Hila Rosenfeld","family":"Keidar","sequence":"first","affiliation":[{"name":"Departments of Pediatric Hemato\u2010Oncology Tel Aviv Medical Center Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Manisterski","sequence":"additional","affiliation":[{"name":"Departments of Pediatric Hemato\u2010Oncology Tel Aviv Medical Center Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Orenstein","sequence":"additional","affiliation":[{"name":"Departments of Pediatric Hemato\u2010Oncology Tel Aviv Medical Center Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Sukhotnik","sequence":"additional","affiliation":[{"name":"Departments of Pediatric Surgery Tel Aviv Medical Center Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5663-6919","authenticated-orcid":false,"given":"Ronit","family":"Elhasid","sequence":"additional","affiliation":[{"name":"Departments of Pediatric Hemato\u2010Oncology Tel Aviv Medical Center Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.1993.8.1.40"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860201)57:3<603::AID-CNCR2820570335>3.0.CO;2-K"},{"key":"e_1_2_7_4_1","first-page":"365","article-title":"Appendicitis in a neutropenic patient: a multicentric retrospective study","volume":"39","author":"Albetro AS","year":"2017","journal-title":"J Pediatr Oncol"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(92)90342-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.09.048"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e318168e7cb"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.1993.8.1.40"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800820207"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2012.53.4.781"},{"key":"e_1_2_7_11_1","article-title":"Acute appendicitis in a child with acute leukemia and chemotherapy\u2010induced neutropenia: a case report and literature review","volume":"12","author":"Alaa A","year":"2020","journal-title":"Cureus"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2017-313267"},{"key":"e_1_2_7_13_1","article-title":"Laparoscopic versus open surgery for suspected appendicitis","volume":"11","author":"Jaschinski T","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-027797"}],"container-title":["Pediatric Blood &amp; 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