{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:20:47Z","timestamp":1792070447958,"version":"4.4.0"},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Implications of repeated resections of pulmonary metastasis (PM) are not well documented in the modern era. Fifteen children underwent two (<jats:italic>n<\/jats:italic>\u00a0=\u00a08), three (<jats:italic>n<\/jats:italic>\u00a0=\u00a03), or four or more (<jats:italic>n<\/jats:italic>\u00a0=\u00a03) resections (total\u00a0=\u00a038 procedures), most commonly for osteosarcoma (71%). Operative approach included muscle\u2010sparing thoracotomy (71%), non\u2010muscle\u2010sparing thoracotomy (18%), and video\u2010assisted thoracoscopy (11%). Median resected nodules per procedure was four (range = 1\u201395). Prolonged air leaks were the most common postoperative complication (29%). Median hospital stay was 4\u00a0days, and no children were discharged with or have required oxygen. Event\u2010free survival is 67% at median follow\u2010up time of 54\u00a0months, with an overall survival rate of 64%. Repeat resection of PM appears to be well tolerated, without prolonged hospital stays or compromised pulmonary function.<\/jats:p>","DOI":"10.1002\/pbc.31304","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T04:18:33Z","timestamp":1725423513000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A modern approach to multiple pulmonary resections in children with recurrent metastatic pulmonary disease"],"prefix":"10.1002","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8581-3726","authenticated-orcid":false,"given":"Nikhil R.","family":"Shah","sequence":"first","affiliation":[{"name":"Section of Pediatric Surgery C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyonna M.","family":"Williams","sequence":"additional","affiliation":[{"name":"Section of Pediatric Surgery C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammy","family":"Stoll","sequence":"additional","affiliation":[{"name":"Section of Pediatric Surgery C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer","family":"Heider","sequence":"additional","affiliation":[{"name":"Department of Pathology C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie P.","family":"Opipari","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rama","family":"Jasty Rao","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika A.","family":"Newman","sequence":"additional","affiliation":[{"name":"Section of Pediatric Surgery C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6161-1815","authenticated-orcid":false,"given":"Peter F.","family":"Ehrlich","sequence":"additional","affiliation":[{"name":"Section of Pediatric Surgery C.S. Mott Children's Hospital  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Geiger","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Nationwide Children's Hospital  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.6491"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24121"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25973"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2016.09.001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33264"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2020.09.060"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181dcf76d"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2022.07.025"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.07.024"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivae028"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.07.039"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010015\u20104682\u20101"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022\u20103468(81)80848\u20102"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)36279-8"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.10.089"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon\u20102020\u20100066"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.31026"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010016\u20104049\u20100"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.10.010"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2023.09.040"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2021.0439"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivt514"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010022\u201012488\u2010y"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.07.65"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.10.024"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2016.10.034"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2016.11.014"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.08.069"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019\u2010016\u20100525\u20109"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010020\u201004683\u20103"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.01.088"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(80)92766\u2010x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2023.0070"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.31304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T13:52:00Z","timestamp":1748353920000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.31304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/pbc.31304"],"URL":"https:\/\/doi.org\/10.1002\/pbc.31304","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,3]]},"assertion":[{"value":"2024-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e31304"}}