{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:28:28Z","timestamp":1787761708755,"version":"build-2784847793"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Survivors of childhood cancer (CCS) and hematopoietic stem cell transplantation (HSCT) recipients are at increased risk of human papillomavirus (HPV)\u2010associated malignancies. Although HPV vaccination is recommended for these groups, parental acceptance remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedure<\/jats:title>\n                    <jats:p>We recruited caregivers of female CCS\/HSCT aged \u22659\u00a0years from the Shanghai Children's Medical Center (SCMC) vaccination clinic. Caregivers of females who were at least 6\u00a0months post treatment, off immunosuppressants, and disease\u2010free were eligible. Caregivers completed a questionnaire assessing demographics, HPV knowledge, and their willingness to vaccinate their daughters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 219 caregivers enrolled, 195 (89.0%) completed the survey. Among the children of caregivers who responded, 44.6% (87\/195) had undergone HSCT. All respondent caregivers lacked awareness that the HPV vaccine was recommended for their daughters. Willingness to vaccinate was endorsed by 65.1% (127\/195) of caregivers, and was significantly associated with a household income over \u00a550,000 (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.02), the mother's HPV vaccination status (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), and their daughter receiving any vaccination post therapy (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.02). The most common reasons for vaccine refusal included concerns about its impact on the child's primary disease (64.7%, 44\/68), vaccine safety (58.8%, 40\/68), and the belief that their child was too young for HPV vaccination (50.0%, 34\/68). Only 15 of the 127 (11.8%) caregivers who initially expressed willingness to vaccinate their children had actually initiated vaccination.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A substantial minority of Chinese caregivers of female CCS\/HSCT are hesitant to vaccinate their daughters against HPV. Addressing caregivers\u2019 knowledge deficits and misperceptions about vaccine safety and barriers to accessing HPV vaccination is important to improve uptake.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pbc.31529","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T23:11:28Z","timestamp":1736291488000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Parental Acceptance of Human Papillomavirus Vaccination Among Females Treated for Childhood Cancer and\/or With Hematopoietic Stem Cell Transplantation: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2051-4044","authenticated-orcid":false,"given":"Jiaoyang","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Hematology &amp; Oncology Shanghai Children's Medical Center Shanghai Jiao Tong University School of Medicine National Children's Medical Center (Shanghai)  Shanghai China"},{"name":"Child Health Advocacy Institute China Hospital Development Institute Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9874-8938","authenticated-orcid":false,"given":"Yin Ting","family":"Cheung","sequence":"additional","affiliation":[{"name":"School of Pharmacy The Chinese University of Hong Kong  Hong Kong SAR China"},{"name":"Hong Kong Hub of Paediatric Excellence The Chinese University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7592-4115","authenticated-orcid":false,"given":"Yijin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Hematology &amp; Oncology Shanghai Children's Medical Center Shanghai Jiao Tong University School of Medicine National Children's Medical Center (Shanghai)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Hematology &amp; Oncology Shanghai Children's Medical Center Shanghai Jiao Tong University School of Medicine National Children's Medical Center (Shanghai)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hematology &amp; Oncology Shanghai Children's Medical Center Shanghai Jiao Tong University School of Medicine National Children's Medical Center (Shanghai)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0303-5658","authenticated-orcid":false,"given":"Ching\u2010Hon","family":"Pui","sequence":"additional","affiliation":[{"name":"Department of Global Pediatric Medicine St. Jude Children's Research Hospital  Memphis Tennessee USA"},{"name":"Department of Oncology St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Deng","sequence":"additional","affiliation":[{"name":"Shanghai Pudong New Area Center for Disease Control  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Fei","sequence":"additional","affiliation":[{"name":"Shanghai Pudong New Area Center for Disease Control  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Shanghai Children's Medical Center Shanghai Jiao Tong University School of Medicine National Children's Medical Center (Shanghai)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa M.","family":"Hudson","sequence":"additional","affiliation":[{"name":"Department of Oncology St. Jude Children's Research Hospital  Memphis Tennessee USA"},{"name":"Department of Epidemiology and Cancer Control St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"WHO Guideline for Screening and Treatment of Cervical Pre\u2010cancer Lesions for Cervical Cancer Prevention","author":"World Health Organization","year":"2021"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2022-070115"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60022-7"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2024.2329450"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1112750"},{"issue":"4","key":"e_1_2_10_7_1","first-page":"287","article-title":"Awareness, Perceptions, and Acceptance of Human Papillomavirus Vaccination Among Parents in Hong Kong","volume":"29","author":"Lam E. 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