{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:44:53Z","timestamp":1783467893329,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high\u2010quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom. Our case series highlighted the value of PET\u2010DOTATATE scans in assisting diagnosis when biopsy was considered high risk. Computed tomography (CT) scan may be useful for demonstrating calcification within the meningioma, a relatively specific finding occurring in 20%\u201350% of ONSM cases. Unfortunately, despite optimal treatment, vision loss is unavoidable in some patients. To improve outcomes, prompt consultation with a multidisciplinary team is recommended.<\/jats:p>","DOI":"10.1002\/pbc.31739","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:35:00Z","timestamp":1745541300000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8047-1870","authenticated-orcid":false,"given":"Deysha","family":"Ratnasingham","sequence":"first","affiliation":[{"name":"Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Lawson","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpreet","family":"Hyare","sequence":"additional","affiliation":[{"name":"University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Gurney","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Apps","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Reekie","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2980-9316","authenticated-orcid":false,"given":"Sucheta","family":"Vaidya","sequence":"additional","affiliation":[{"name":"Royal Marsden Hospital Sutton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Soto","sequence":"additional","affiliation":[{"name":"University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavitha","family":"Srivatsa","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslaw","family":"Peregud\u2010Pogorzelski","sequence":"additional","affiliation":[{"name":"Pomeranian Medical University Szczecin Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Brodkiewicz","sequence":"additional","affiliation":[{"name":"Pomeranian Medical University Szczecin Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owase","family":"Jeelani","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Jorgensen","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarita","family":"Depani","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Hargrave","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"},{"name":"University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elwira","family":"Szychot","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital London UK"},{"name":"Pomeranian Medical University Szczecin Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/02688697.2020.1726286"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310672"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(92)90135-G"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-199203210-00017"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00787-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1723801"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000700"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S82795"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2008.08.022"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2273010758"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25614"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13132307"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-23-2533"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/now001"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(90)32538-1"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.114.149120"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.124.3.379"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.31739","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pbc.31739","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.31739","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T23:50:23Z","timestamp":1775865023000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.31739"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/pbc.31739"],"URL":"https:\/\/doi.org\/10.1002\/pbc.31739","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,24]]},"assertion":[{"value":"2024-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e31739"}}