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We evaluated long\u2010term outcomes of infants with suspected perinatal neuroblastoma enrolled on the Children's Oncology Group (COG) ANBL00P2, which included an expectant observation approach. Among 87 eligible patients, the 10\u2010year event\u2010free survival (EFS) was 93.7%, and overall survival (OS) was 98.0%. Most tumors regressed spontaneously; only three patients reported progression to higher stage disease. This report reinforces the long\u2010term safety of non\u2010interventional management in perinatal neuroblastoma, sparing infants unnecessary surgery and associated risks.<\/jats:p>","DOI":"10.1002\/pbc.31829","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:34:17Z","timestamp":1748824457000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Long\u2010Term Outcome of Young Infants With Suspected Neuroblastoma following Observation as Primary Therapy: A Report From the Children's Oncology Group"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1713-3822","authenticated-orcid":false,"given":"Hetal","family":"Dholaria","sequence":"first","affiliation":[{"name":"Department of Oncology Perth Children's Hospital  Perth Australia"},{"name":"WA Kids Cancer Center The Kids Research Institute Australia  Perth Australia"},{"name":"The University of 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