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This study aimed to describe the health\u2010related, psychosocial late effects, and information needs among CCSs in the region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This mixed\u2010method study combined quantitative data from an online survey with qualitative insights from follow\u2010up interviews, involving CCSs from the largest regional survivor network and additional participants recruited through snowball sampling. We report the quantitative results here. The survey was adapted from the Childhood Cancer Survivor Study Survey Follow\u2010Up and the Needs Assessment Questionnaire (CCSS\u2010NAQ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 135 CCSs from 16 Latin American countries participated (mean age 26.1 years). The most frequent late effects were mental health (61.2%), endocrine (58.6%), and cardiovascular (42.1%). Infertility was prevalent (16.9%), with nearly one\u2010third unsure of their fertility status. Anxiety (51.1%) and depression (31.8%) were common. Significant findings included higher rates of endocrine disorders in females (<jats:italic>p<\/jats:italic> = 0.0018) and those who had received radiation (<jats:italic>p<\/jats:italic> = 0.048), respiratory problems in stem cell transplantation recipients (<jats:italic>p<\/jats:italic> = 0.026), and auditory impairment in survivors of a solid tumor (<jats:italic>p<\/jats:italic> = 0.0031). While most felt informed about their health, only one\u2010third had regular medical follow\u2010up and access to psychological care. Survivors expressed a strong interest in learning more about fertility and mental health, with a preference for digital information.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study documents the need for region\u2010specific survivorship care that addresses both the physical and mental health challenges of Latin American CCSs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.31833","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T10:10:12Z","timestamp":1749809412000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Childhood Cancer Survivors in Latin America: Insights Into Health Outcomes and Information Needs"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9161-6147","authenticated-orcid":false,"given":"Ana Carolina","family":"Izurieta\u2010Pacheco","sequence":"first","affiliation":[{"name":"Oncology 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