{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T01:02:25Z","timestamp":1776474145428,"version":"3.51.2"},"reference-count":57,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008363","name":"Kr\u00e6ftens Bek\u00e6mpelse","doi-asserted-by":"publisher","award":["R173\u2010A11326\u201017\u2010551"],"award-info":[{"award-number":["R173\u2010A11326\u201017\u2010551"]}],"id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007403","name":"Dagmar Marshalls Fond","doi-asserted-by":"publisher","award":["500020"],"award-info":[{"award-number":["500020"]}],"id":[{"id":"10.13039\/100007403","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010727","name":"Axel Muusfeldts Fond","doi-asserted-by":"publisher","award":["2019\u20100137"],"award-info":[{"award-number":["2019\u20100137"]}],"id":[{"id":"10.13039\/100010727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005860","name":"Helsefonden","doi-asserted-by":"publisher","award":["19\u2010B\u20100045"],"award-info":[{"award-number":["19\u2010B\u20100045"]}],"id":[{"id":"10.13039\/501100005860","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Home death may not be equally accessible for all children with incurable cancer. Furthermore, inadequate symptom management in the home setting represents a major concern. The aims of this study were to examine: (i) the associations between parents\u2019 sociodemographic characteristics, prognostic understanding and care goals, and their child's place of death; and (ii) the associations between the child's place of death, and the parents\u2019 experiences of their child's symptom burden, end\u2010of\u2010life, and death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nationwide retrospective cross\u2010sectional survey among bereaved parents (<jats:italic>n<\/jats:italic> = 117) of children who died from cancer (<jats:italic>n<\/jats:italic> = 96) in Denmark at age younger than 18\u00a0years in the period 2006\u20132019. Data were analyzed using logistic regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Parents who realized that their child had no realistic chance of cure \u22651\u00a0month before death had greater odds that their child died at home (odds ratio [OR] = 6.8; 95% confidence interval [CI]: 1.5\u201331.9; adjusted for child's cancer type, and parent's education, cohabitation status, and care goals). Parents whose child died at home were less likely to report a high symptom burden (OR = 0.4; CI: 0.2\u20130.9), and to prefer another place of death in hindsight (OR = 0.03; CI: 0.004\u20130.3), and more likely to feel prepared at the time of death (OR = 2.5; CI: 1.1\u20135.7), and to report that their child experienced a \u201cgood death\u201d (OR = 3.4; CI: 1.2\u20139.6) (all ORs adjusted for child's cancer type).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>When a child's death from cancer is foreseen and prepared for, the child's symptoms can be managed at home. Furthermore, parents whose child died at home had more positive experiences of their child's end\u2010of\u2010life and death.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.31878","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T01:54:53Z","timestamp":1751594093000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Parental Perspectives on Location of Death for Children With Cancer \u2010 A Nationwide Cross\u2010sectional Survey of Bereaved Parents"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2103-1204","authenticated-orcid":false,"given":"Nanna Maria","family":"Hammer","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Copenhagen University Hospital \u2010 Rigshospitalet  Copenhagen Denmark"},{"name":"Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pernille Envold","family":"Bidstrup","sequence":"additional","affiliation":[{"name":"Psychological Aspects of Cancer, Cancer Survivorship Danish Cancer Institute  Copenhagen Denmark"},{"name":"Institute of Psychology University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Rosth\u00f8j","sequence":"additional","affiliation":[{"name":"Statistics and Data Analysis Danish Cancer Institute  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Abitz","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Copenhagen University Hospital \u2010 Rigshospitalet  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Thude","family":"Callesen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Odense University Hospital  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa Lyngsie","family":"Hjalgrim","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Copenhagen University Hospital \u2010 Rigshospitalet  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pernille Wendtland","family":"Edslev","sequence":"additional","affiliation":[{"name":"Paediatric and Adolescent Health Center for Paediatric Oncology and Haematology Team for Palliative Care Aarhus University Hospital  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Wolfe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Massachusetts General and Brigham and Women's Hospitals Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanne B\u00e6kgaard","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Copenhagen University Hospital \u2010 Rigshospitalet  Copenhagen Denmark"},{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine Copenhagen University Hospital \u2010 Rigshospitalet  Copenhagen Denmark"},{"name":"Department of Pediatrics and Adolescent Medicine Section of Pediatric Hematology and Oncology Aalborg University Hospital  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.12.370"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colegn.2014.07.001"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24872"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25358"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20220070"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431\u2010020\u201003689\u20102"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431\u2010021\u201004250\u20105"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010016\u20102695\u20101"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.03.030"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904\u2010020\u201000672\u20104"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0030222820959941"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/OP.20.00958"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2020.07.018"},{"key":"e_1_2_7_15_1","unstructured":"K.Das T.Khanna A.Arora andN.Agrawal \u201cParents' acceptance and Regret About End of Life Care for Children Who Died due to Malignancy \u201d Supportive Care in Cancer https:\/\/doi.org\/10.1007\/s00520\u2010019\u201004806\u20100."},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.284"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/15360288.2014.911801"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2021.12.031"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904\u2010022\u201001078\u20100"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2023.02.006"},{"key":"e_1_2_7_21_1","volume-title":"EAPC Atlas of Palliative Care in Europe 2019","author":"Arias\u2010Casais N.","year":"2019"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390\u2010021\u201001909\u20105"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25479"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2007.12.017"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269216306pm1139oa"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216320967547"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-61391-8_4"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0031\u20103955(02)00034\u20102"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.19.2469"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(07)70209\u20107"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.4659"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2022.12.004"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/26323524231193036"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.09.007"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_7_36_1","unstructured":"\u201cSundhedsdatastyrelsen [The Danish Health Data Authority] \u201dThe Danish Health Data Authority accessed June 21 2023 https:\/\/sundhedsdatastyrelsen.dk\/da\/forskerservice."},{"key":"e_1_2_7_37_1","volume-title":"International Statistical Classification of Diseases and Related Health Problems, 10th Revision","author":"World Health Organization","year":"2004"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811399958"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200002033420506"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524\u20104733.2005.04054.x"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.4135\/9781412983655"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.4300\/JGME\u2010D\u201013\u201000154.1"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.06.025"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare\u20102021\u2010003251"},{"key":"e_1_2_7_47_1","unstructured":"R Core Team \u201cR: A Language and Environment for Statistical Computing \u201dR Foundation for Statistical Computing 2022 https:\/\/www.R\u2010project.org\/."},{"key":"e_1_2_7_48_1","unstructured":"Dansk B\u00f8rnecancer Register \u201cDansk B\u00f8rnecancer Register; National \u00c5rsrapport for Perioden 01.01.2022\u201331.12.2022 [Danish Childhood Cancer Registry; National Annual Report for the Period 01.01.2022\u201331.12.2022] \u201dRegionernes kliniske kvalitetsudviklingsprogram (RKKP) 2023."},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2022.12.139"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1177\/02692163221135350"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.7645"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.69.1634"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010019\u201004933\u20108"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.08.557"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010019\u201004806\u20100"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/hsc.12512"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1200\/OP.22.00538"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2022.12.144"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.31878","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T03:33:31Z","timestamp":1753241611000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.31878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,3]]},"references-count":57,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/pbc.31878"],"URL":"https:\/\/doi.org\/10.1002\/pbc.31878","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,3]]},"assertion":[{"value":"2024-06-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e31878"}}