{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:05:19Z","timestamp":1782489919487,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T00:00:00Z","timestamp":1756598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA225629"],"award-info":[{"award-number":["R01 CA225629"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["TCA136432C T32"],"award-info":[{"award-number":["TCA136432C T32"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Adolescents and young adults (AYAs) receiving hematopoietic cell transplantation (HCT) for malignancy are at risk for poor psychological outcomes. Promoting Resilience in Stress Management (PRISM) is an early palliative care intervention that has previously been evaluated in a randomized trial among AYAs receiving HCT; results suggested the intervention's effect was limited to AYAs with baseline psychological symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We performed a post hoc analysis of these same data to explore differences in response based on sociodemographic factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>AYA participants were eligible for the trial if they were 12\u201324\u00a0years old, English\u2010speaking, cognitively able, and within 4\u00a0weeks of HCT for malignancy or bone marrow failure. Enrolled AYAs reported their symptoms of anxiety, depression, hope, cancer\u2010related quality of life, and resilience using standardized instruments at baseline and 6\u00a0months. We explored intervention effect sizes (Cohen's <jats:italic>d<\/jats:italic>) among groups stratified by gender, age, race, zip\u2010code\u2010based community distress (Distressed Community Index, with scores 3\u20135 indicating distressed communities), and baseline psychological symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 94 participants (50 PRISM, 44 Usual Care), 46% were female, 44% were 18\u201324\u00a0years old, 60% identified as non\u2010Latino White, and 49% lived within distressed communities. Among AYAs 18\u201324\u00a0years old, those with baseline psychological distress tended toward gaining resilience, while those without baseline psychological symptoms seemed to gain hope. AYAs of all ages from distressed communities and with high baseline psychological burden seemed to gain both resilience and hope.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>AYAs with different ages, backgrounds, and psychological symptoms may have different responses to programs like PRISM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Trial Registration Number<\/jats:title><jats:p>NCT03668223.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.31998","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T06:26:02Z","timestamp":1756707962000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Examining Sociodemographic Differences in Response to Resilience Coaching for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation\u2014A Post Hoc Analysis of the PRISM Intervention"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3031-9632","authenticated-orcid":false,"given":"Adam Ren\u00e9 P.","family":"Rosenbaum","sequence":"first","affiliation":[{"name":"Dana Farber\/Boston Children's Cancer and Blood Disorders Center  Boston Massachusetts USA"},{"name":"Department of Supportive Oncology Dana Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly","family":"Ream","sequence":"additional","affiliation":[{"name":"Department of Supportive Oncology Dana Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5434-7980","authenticated-orcid":false,"given":"Kaitlyn M.","family":"Fladeboe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Washington School of Medicine  Seattle Washington USA"},{"name":"Ben Towne Center For Childhood Cancer and Blood Disorders Research Seattle Children's Research Institute  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Lau","sequence":"additional","affiliation":[{"name":"Seattle Children's Research Institute  Seattle Washington USA"},{"name":"Department of Psychiatry and Behavioral Sciences University of Washington School of Medicine  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce P.","family":"Yi\u2010Frazier","sequence":"additional","affiliation":[{"name":"Department of Supportive Oncology Dana Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abby R.","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Dana Farber\/Boston Children's Cancer and Blood Disorders Center  Boston Massachusetts USA"},{"name":"Department of Supportive Oncology Dana Farber Cancer Institute  Boston 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