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This single\u2010center retrospective cohort study describes 24 pediatric patients with solid tumors who initiated romiplostim a median of 5\u00a0months into chemotherapy (range: 0\u201314\u00a0months) at a median maximum dose of 6.5\u00a0\u00b5g\/kg (range: 1\u201310). A minority of patients achieved a decrease in cycle delays (30%) or dose reductions (13%). A comparative cohort, which did not receive romiplostim, had no difference in cycle delays (<jats:italic>p<\/jats:italic> = 0.42) or dose reductions (<jats:italic>p<\/jats:italic> &gt; 0.99). There were no adverse events. 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