{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:01:08Z","timestamp":1781715668687,"version":"3.54.5"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytochemical Analysis"],"published-print":{"date-parts":[[2020,9]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n It is important to conduct studies on the influence of environmental factors on the accumulation of secondary metabolites in plants, as well as the cultivation of plants and harvesting of their raw material.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n In this study, we examined the influence of habitat types, soil composition, climatic factors and altitude on the content of phenolic compounds in\n Iris<\/jats:italic>\n species from different populations in Latvia, Lithuania and Ukraine.\n <\/jats:p>\n <\/jats:sec>\n \n Methodology<\/jats:title>\n \n According to high\u2010performance liquid chromatography (HPLC) analysis, 25 compounds (flavonoids, isoflavonoids, isoflavonoid glucosides, xanthones, phenolcarboxylic acids) were identified in the methanol extracts of 16 samples of\n Iris<\/jats:italic>\n rhizomes. The quantitative data were further analysed by principal component analysis (PCA) to reveal the impact of environmental factors on the accumulation of compounds in plants.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n Iris pseudacorus<\/jats:italic>\n <\/jats:styled-content>\n from Latvia and Lithuania had a more diverse composition of phenolic compounds than samples from Ukraine. Sampled plants of the\n Iris<\/jats:italic>\n subg.\n Iris<\/jats:italic>\n had a higher content of the analysed compounds than those of\n Iris<\/jats:italic>\n subg.\n Limniris.<\/jats:italic>\n PCA results showed that the levels of phenolic compounds in\n Iris<\/jats:italic>\n rhizomes were influenced by the content of soil nutrients. The phosphorus and potassium content had a significant impact on the levels of phenolic compounds, whereas the impact of nitrogen content was not significant. Meteorological factors had a small impact; however, sunshine duration had a significant positive effect and the amount of precipitation had a significant negative impact.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The results of this study suggest that rhizomes of\n Iris<\/jats:italic>\n species may be an important source of pharmacologically active compounds such as flavonoids, isoflavonoids and xanthones. Studies on the effect of environmental factors on the production and accumulation of secondary metabolites in\n Iris<\/jats:italic>\n species are important because they contribute to knowledge of quantitative parameters of secondary metabolites in medicinal plants and could be employed for the cultivation and harvesting of raw material for medicinal purposes.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/pca.2918","type":"journal-article","created":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T02:15:32Z","timestamp":1579659332000},"page":"545-563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Effect of ecological factors on the accumulation of phenolic compounds in\n Iris<\/i>\n species from Latvia, Lithuania and Ukraine"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3822-8409","authenticated-orcid":false,"given":"Olha","family":"Mykhailenko","sequence":"first","affiliation":[{"name":"Department of Botany National University of Pharmacy Valentynivska Str. 4 Kharkiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6230-5924","authenticated-orcid":false,"given":"Zigmantas","family":"Gud\u017einskas","sequence":"additional","affiliation":[{"name":"Nature Research Centre Institute of Botany \u017dali\u0173j\u0173 E\u017eer\u0173 Str. 49 Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7852-7783","authenticated-orcid":false,"given":"Volodymyr","family":"Kovalyov","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy National University of Pharmacy Valentynivska Str. 4 Kharkiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volodymyr","family":"Desenko","sequence":"additional","affiliation":[{"name":"Kharkiv Branch of the State Institution Soil Protection Institute of Ukraine Kosmichna Str. 21A Kharkiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5390-2161","authenticated-orcid":false,"given":"Liudas","family":"Ivanauskas","sequence":"additional","affiliation":[{"name":"Department of Analytical and Toxicological Chemistry Lithuanian University of Health Sciences A. Mickevi\u010diaus Str. 9 Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1212-1649","authenticated-orcid":false,"given":"Ivan","family":"Bezruk","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry National University of Pharmacy Valentynivska Str. 4 Kharkiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoriya","family":"Georgiyants","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry National University of Pharmacy Valentynivska Str. 4 Kharkiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,21]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2012.07.002"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules191016240"},{"key":"e_1_2_4_4_1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/978-981-13-0535-1","volume-title":"Biotechnological approaches for medicinal and aromatic plants: Conservation, genetic improvement and utilization","author":"Kumar N","year":"2018"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.3410\/B3-16"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4161\/psb.6.11.17613"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep28591"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122981"},{"key":"e_1_2_4_9_1","first-page":"397","volume-title":"Flavonoids: Chemistry, biochemistry and applications","author":"Gould KS","year":"2006"},{"key":"e_1_2_4_10_1","first-page":"12","article-title":"Roles of flavonoids in plants","volume":"6","author":"Samanta A","year":"2011","journal-title":"Int J Pharm Sci Tech"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2012.07.014"},{"key":"e_1_2_4_12_1","first-page":"27","article-title":"Flavones: from biosynthesis to health benefits","volume":"5","author":"Jiang N","year":"2016","journal-title":"Plan Theor"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3040.2010.02154.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2015.00939"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.4161\/gmcr.29436"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)91082-3"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fix022"},{"key":"e_1_2_4_18_1","first-page":"39","article-title":"Micro\u2010elements in agriculture. 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