{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T20:33:28Z","timestamp":1776285208602,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T00:00:00Z","timestamp":1644192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81573543"],"award-info":[{"award-number":["81573543"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81773853"],"award-info":[{"award-number":["81773853"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytochemical Analysis"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Astragali Radix has been used for over 2000\u2009years in traditional Chinese medicine. Its secondary xylem \u201cJinjing\u201d and secondary phloem \u201cYulan\u201d are important for evaluating the quality of the Daodi medicinal material in China. However, its systematic characterisation has not been conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to investigate the colour, chemical compounds, and antioxidant capacity of the secondary xylem and phloem of Astragali Radix on the basis of untargeted metabolomics, broadening the application scope of Astragali Radix in food and pharmaceutical industries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:italic>L*<\/jats:italic>, <jats:italic>a*<\/jats:italic>, and <jats:italic>b*<\/jats:italic> of the secondary xylem and phloem were measured by colorimetry, and the chemical compounds were identified and quantified by ultra\u2010performance liquid chromatography\u2010quadrupole\u2010time\u2010of\u2010flight mass spectrometry (UPLC\u2010Q\u2010TOF\u2010MS) and high\u2010performance liquid chromatography\u2010diode array detector\u2010evaporative light scattering detection. 2,2\u2010Diphenyl\u20101\u2010picrylhydrazyl (DPPH) and 2\u2010azino\u2010bis\u2010(3\u2010ethylbenzothiazoline\u20106\u2010sulphonic acid) (ABTS) assays were conducted to evaluate their antioxidant capacity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010one compounds were identified by UPLC\u2010Q\u2010TOF\u2010MS. The secondary xylem exhibited high parameter <jats:italic>b*<\/jats:italic>, flavonoid content, and antioxidant capacity, while the secondary phloem was rich in astragalosides. The colour parameters of well\u2010defined type A significantly varied from those of the other types. Well\u2010defined type A also exhibited the highest antioxidant activity and flavonoid content, followed by middle type A\u2010like, middle type B\u2010like, and yellow shading type B.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The colour parameters, chemical compounds, and antioxidant capacity among the different transverse sections of secondary xylem and phloem varied. The yellow colour of secondary xylem was correlated to high flavonoid content and antioxidant activity, and well\u2010defined type A of Astragali Radix had better quality than other types.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pca.3113","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T02:56:08Z","timestamp":1644288968000},"page":"599-611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Colour, chemical compounds, and antioxidant capacity of Astragali Radix based on untargeted metabolomics and targeted quantification"],"prefix":"10.1002","volume":"33","author":[{"given":"Mei","family":"Yang","sequence":"first","affiliation":[{"name":"National Resource Centre for Chinese Materia Medica China Academy of Chinese Medical Sciences  Beijing China"},{"name":"School of Pharmacy Anhui University of Chinese Medicine  Hefei 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