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This study aimed to identify heterogeneous classes of comorbid depression and anxiety (CDA) among older people in China and to ascertain predictors of latent class membership. Cross\u2010sectional data of 10,919 cases were extracted from the Chinese Longitudinal Healthy Longevity Survey. Latent profile analysis (LPA) was used to identify symptom patterns of comorbid depression (measured by the 10\u2010item Center for Epidemiologic Studies Depression Scale) and anxiety (measured by the Generalized Anxiety Disorder 7\u2010item Scale). Multinomial logistic regressions following bivariate analyses were used to explore the relationship between the derived classes and individual\u2010 and social\u2010level factors. Four patterns of CDA were identified: low symptoms of depression and anxiety (30.52%;\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20093333), mild depression only (53.26%;\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20095815), moderate depression and anxiety (13.82%;\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20091509), and severe depression and anxiety (2.40%;\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009262). Older people who are male, suffer from multimorbidity, and lack a healthy lifestyle are more likely to have problematic symptom profiles. While intimate relationships with partners and children significantly predicted CDA patterns, the effects of sibling relationships, daily life, and emotional support from the community were insignificant. LPA identified four distinct CDA patterns among a representative sample of older Chinese people. While restless sleep, lack of positive emotions, uselessness, and weak concentration are salient across all profiles, \u201cdifficult to relax\u201d is prominent in profiles high in anxiety. In addition to individual\u2010level variables, social\u2010level factors, especially intimate relationships with partners and children rather than general links to siblings or the community, have unneglectable impacts on whether and to what extent older Chinese adults suffer from CDA in the cultural context of relationism, patriarchy, and filial piety.\n                  <\/jats:p>","DOI":"10.1002\/pchj.729","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T23:54:49Z","timestamp":1706140489000},"page":"494-511","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Symptom patterns of comorbid depression and anxiety among older adults in China and their predictors"],"prefix":"10.1002","volume":"13","author":[{"given":"Lingling","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Philosophy and Science Southeast University at Nanjing  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-2209","authenticated-orcid":false,"given":"Chuqian","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medical Humanities Southeast University at Nanjing  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16111918"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-3797(18)30622-6"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.157.1.89"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e32833f305f"},{"key":"e_1_2_9_6_1","unstructured":"Center for Healthy Aging and Development Studies. 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