{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:36:43Z","timestamp":1787240203828,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PCN Reports"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Obsessive\u2013compulsive disorder (OCD) is a common neuropsychiatric disorder affecting many behaviors in daily life. Hyperactivity of the fronto\u2010striato\u2010thalamic circuit via the orbitofrontal cortex (OFC) is assumed to play a major role in the pathophysiology of OCD; however, its pathogenesis is not fully understood. Several reports have described the development of OCD after traumatic brain injury (TBI); however, the pathogenesis of post\u2010TBI OCD remains unknown. Moreover, patients with TBI often have a variety of sequelae, including cognitive dysfunction and mood disorders, which make the diagnosis and treatment of OCD more complex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report the case of a 17\u2010year\u2010old Japanese male who developed OCD after traffic trauma. The patient developed a fear of contamination and checking compulsion after injuring his right OFC and left temporal lobe when he ran into a running truck during a suicide attempt. We believe that the patient's fear of contamination can be diagnosed as true post\u2010TBI OCD. However, his memory impairment was significant, and we considered his checking compulsion to be strongly influenced by cognitive dysfunction due to TBI. We attempted behavioral therapy for OCD; however, sufficient results were not achieved because of the interference from the sequelae of TBI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>It is not rare for OCD symptoms to appear after TBI. Differentiating the OCD symptoms induced by brain injury or cognitive dysfunction associated with TBI is important to determine a treatment strategy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pcn5.199","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T06:45:30Z","timestamp":1718347530000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Obsessive\u2013compulsive disorder after traumatic injury to the right frontal and left temporal lobes: A case report"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9775-2369","authenticated-orcid":false,"given":"Daisuke","family":"Yoshioka","sequence":"first","affiliation":[{"name":"Division of Neuropsychiatry Faculty of Medicine, Tottori University Yonago Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3881-8997","authenticated-orcid":false,"given":"Takehiko","family":"Yamanashi","sequence":"additional","affiliation":[{"name":"Division of Neuropsychiatry Faculty of Medicine, Tottori University Yonago Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7581-9443","authenticated-orcid":false,"given":"Teruaki","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Division of Neuropsychiatry Faculty of Medicine, Tottori University Yonago Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Iwata","sequence":"additional","affiliation":[{"name":"Division of Neuropsychiatry Faculty of Medicine, Tottori University Yonago Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2007.09.005"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2015.08.017"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1364-6613(98)01231-5"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(03)00168-9"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.174.4.360"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/026990596124340"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/026990596124728"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.20398"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.47.2.353"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/13803395.2013.863832"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/02699059509004566"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.144.2.190"},{"issue":"2","key":"e_1_2_12_14_1","first-page":"371","article-title":"Evidence for striatal modulation in the presence of fixed cortical injury in obsessive\u2013compulsive disorder (OCD)","volume":"9","author":"Hendler T","year":"1999","journal-title":"Eur Neuropsychopharmacol"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psycr.2023.100176"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S109285291500053X"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540260310001606737"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.2190\/XENN-NNWT-7N2K-R26A"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2019.08.004"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/jehp.jehp_812_20"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.48.5.448"},{"key":"e_1_2_12_22_1","first-page":"797","article-title":"Psychiatric disorders and traumatic brain injury","volume":"4","author":"Schwarzbold M","year":"2008","journal-title":"Neuropsychiatr Dis Treat"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.4236\/psych.2021.123022"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.01.005"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7967(02)00012-8"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2004.04.007"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1556-07.2007"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.04.004"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/10.3.308"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2004.11.006"},{"key":"e_1_2_12_31_1","article-title":"Treatments for Obsessive\u2010Compulsive Disorder in Patients with Traumatic","volume":"25","author":"Drake T","year":"2022","journal-title":"Brain Injury: A Systematic Review. 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