{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T15:10:58Z","timestamp":1771168258279,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:00:00Z","timestamp":1760227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:00:00Z","timestamp":1760227200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PCN Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Managing bipolar disorder during pregnancy requires balancing maternal mental health and fetal safety. While guidelines often focus on severe mania, the management of hypomania, a common clinical challenge, remains poorly defined. Although shared decision\u2010making (SDM) is recommended for treatment planning, its application in managing acute mood episodes during pregnancy remains underexplored, especially without robust evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A woman in her thirties with DSM\u20105 Bipolar I Disorder developed a hypomanic episode at 32 weeks of gestation while on aripiprazole once\u2010monthly (AOM) 400\u2009mg monotherapy. Although antipsychotic augmentation was considered, limited evidence and strong patient and family concerns regarding fetal exposure led to an SDM\u2010based approach. The AOM monotherapy was continued with intensive monitoring. Hypomanic symptoms resolved within 4 weeks (Young Mania Rating Scale scores decreased from 14 to 1), with corresponding improvements in functional scores (Global Assessment of Functioning and the Social and Occupational Functioning Assessment Scale), and the patient delivered a healthy infant at term. She remained euthymic at 7 months postpartum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SDM, when combined with intensive measurement\u2010based care, may effectively manage acute hypomanic episodes during pregnancy. This case demonstrates that a conservative approach, guided by SDM, can be a viable strategy for managing pregnancy\u2010related hypomania, highlighting the importance of an individualized treatment plan that respects patient values in a clinical setting with limited evidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pcn5.70225","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T05:07:42Z","timestamp":1760332062000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of aripiprazole long\u2010acting injection monotherapy in pregnancy\u2010related hypomania: A treatment choice through shared decision\u2010making"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4626-4218","authenticated-orcid":false,"given":"Yoshiyo","family":"Oguchi","sequence":"first","affiliation":[{"name":"Department of Neuropsychiatry St. Marianna University School of Medicine Miyamae\u2010ku Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2294-2571","authenticated-orcid":false,"given":"Atsuo","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry St. Marianna University School of Medicine Miyamae\u2010ku Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Kocha","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry St. Marianna University School of Medicine Miyamae\u2010ku Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.06101639"},{"key":"e_1_2_12_3_1","first-page":"7","article-title":"Treatment of bipolar disorders during pregnancy: maternal and fetal safety and challenges","volume":"7","author":"Epstein RA","year":"2015","journal-title":"Drug Healthc Patient Saf"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1109283"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126073"},{"key":"e_1_2_12_6_1","volume-title":"Clinical guide for women with mental health problems during perinatal period","author":"Japanese Society of Psychiatry and Neurology, Japan Society of Obstetrics and Gynecology; Clinical Practice Guidelines for Pregnant Women and Women in Labor with Comorbid Mental Disorders or at Risk of Comorbidity","year":"2020"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12609"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.20ac13597"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40360-019-0330-x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000001773"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20043080"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semperi.2020.151230"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2019.19030228"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2019.1617847"}],"container-title":["Psychiatry and Clinical Neurosciences Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pcn5.70225","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pcn5.70225","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pcn5.70225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T14:46:30Z","timestamp":1771166790000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pcn5.70225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,12]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/pcn5.70225"],"URL":"https:\/\/doi.org\/10.1002\/pcn5.70225","archive":["Portico"],"relation":{},"ISSN":["2769-2558","2769-2558"],"issn-type":[{"value":"2769-2558","type":"print"},{"value":"2769-2558","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,12]]},"assertion":[{"value":"2025-08-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70225"}}