{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:57:19Z","timestamp":1790679439224,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PCN Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>While \u201ccontrolled drinking\u201d as a treatment goal for alcohol use disorder (AUD) has recently become accepted in Japan, knowledge regarding the clinical characteristics and drinking patterns of patients with AUD remains limited. This study aimed to describe the gender\u2010stratified baseline clinical characteristics and drinking patterns of treatment\u2010seeking patients with AUD using baseline data from the Alcohol Longitudinal Prognosis Study in Japan (ALPS\u2010J), a multicenter cohort study conducted at 15 facilities nationwide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The diagnosis and severity of AUD were assessed using the Structured Clinical Interview for DSM\u20105 Research Version (SCID\u20105\u2010RV). Depressive symptoms were assessed using the Patient Health Questionnaire\u20109 (PHQ\u20109). Sleep quality was assessed using the Japanese version of the Pittsburgh Sleep Quality Index (PSQI\u2010J). Drinking patterns were assessed using an original questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 354 participants were analyzed; 83.1% were male, the mean age was 51.9\u2009\u00b1\u200911.2 years, and 85.0% were inpatients. Overall, 80.8% met the diagnostic criteria for severe AUD. Treatment was started approximately 5 years after the onset of drinking problems. Comorbid depressive symptoms were observed in 44.7% of participants, and 74.3% reported poor sleep quality. The mean daily pure alcohol consumption was 110.4\u2009g. The most commonly consumed type of alcoholic beverage was chu\u2010hai with 9% alcohol by volume, a high\u2010alcohol beverage commonly sold in Japan and often referred to as \u201cstrong\u2010style\u201d chu\u2010hai.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with AUD treated in specialized addiction treatment facilities often present with severe and complex clinical profiles, highlighting the need for earlier engagement in care and integrated treatment approaches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pcn5.70379","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T11:52:41Z","timestamp":1786103561000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical characteristics and drinking patterns among treatment\u2010seeking patients with alcohol use disorder in Japan from the ALPS\u2010J nationwide prospective cohort study"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3733-0110","authenticated-orcid":false,"given":"Chie","family":"Nitta","sequence":"first","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"},{"name":"Institute of Medicine University of Tsukuba Tsukuba Ibaraki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moemi","family":"Shibasaki","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9077-6593","authenticated-orcid":false,"given":"Yuko","family":"Urayama","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Yumoto","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Maesato","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Ryukyu Hospital Kunigami Okinawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"Muto","sequence":"additional","affiliation":[{"name":"Koyodai Hospital Kumamoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhei","family":"Amano","sequence":"additional","affiliation":[{"name":"Psychiatry Anzunokai Kakamigahara Hospital Kakamigahara Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Koga","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4471-5799","authenticated-orcid":false,"given":"Tomomi","family":"Toyama","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9838-350X","authenticated-orcid":false,"given":"Ryuhei","family":"So","sequence":"additional","affiliation":[{"name":"Okayama Psychiatric Medical Center Okayama Japan"},{"name":"Department of Public Health Promotion and Human Behavior Kyoto University Graduate School of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Okayama Psychiatric Medical Center Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Ohishi","sequence":"additional","affiliation":[{"name":"Ohishi Clinic Yokohama Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Minami","sequence":"additional","affiliation":[{"name":"Funabashi Kita Hospital Funabashi Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Kimura","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachio","family":"Matsushita","sequence":"additional","affiliation":[{"name":"National Hospital Organization, Kurihama Medical and Addiction Center Yokosuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,7]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"World Health Organization. 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