{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:57:24Z","timestamp":1790679444862,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PCN Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Few studies in Japan have described young patients presenting to emergency departments after dextromethorphan overdose in detail. Therefore, we aimed to investigate the demographic characteristics and psychosocial backgrounds of patients who presented to emergency departments in Japan after dextromethorphan overdose.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a multicenter, prospective, observational study with nonconsecutive enrollment. A standardized questionnaire regarding dextromethorphan overdose and the Drug Abuse Screening Test\u201020 (DAST\u201020) were administered in eight emergency departments in Japan. Continuous variables are presented as medians and interquartile ranges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 78 patients were included. The median age was 20 years (17.0\u201322.0), and 64 patients (82.1%) were female. Fifty\u2010six (71.8%) patients engaged in social activities. Fifty\u2010one patients (65.4%) stated that the purpose of the overdose was suicide\/self\u2010harm. The number of patients who reported that the source of information on dextromethorphan overdose was social networking services and internet searches was 27 (35.1%) and 29 (37.7%), respectively. Fifty\u2010eight patients (74.4%) reported that dextromethorphan was purchased from a retail store. Among 66 respondents, 40 (60.6%) had moderate or higher DAST\u201020 scores. On comparing the younger group aged 10\u201319 years (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200938) and the older group aged \u226520 years (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200940), the number of patients who indicated that the source of information on dextromethorphan overdose was internet searches in the former group (19, 50.0%) was significantly higher than that in the latter group (10, 25.0%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dextromethorphan overdose predominantly involved young women, and drug\u2010related problems were common.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pcn5.70406","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T13:02:25Z","timestamp":1788440545000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Demographic characteristics and psychosocial backgrounds of patients with dextromethorphan overdose in Japan: A multicenter prospective observational study"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1112-4315","authenticated-orcid":false,"given":"Hironori","family":"Katsuki","sequence":"first","affiliation":[{"name":"Department of Clinical Toxicology Saitama Medical University Hospital Iruma\u2010gun Saitama Japan"},{"name":"Department of Emergency Medicine Iizuka Hospital Iizukashi Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshito","family":"Kamijo","sequence":"additional","affiliation":[{"name":"Department of Clinical Toxicology Saitama Medical University Hospital Iruma\u2010gun Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiko","family":"Takai","sequence":"additional","affiliation":[{"name":"Department of Clinical Toxicology Saitama Medical University Hospital Iruma\u2010gun Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5924-979X","authenticated-orcid":false,"given":"Saeko","family":"Kohara","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine and Trauma National Hospital Organization Disaster Medical Center Tokyo Tachikawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetada","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nara Medical University Kashihara Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Maebashi Red Cross Hospital Maebashi Gunma Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidenobu","family":"Ochiai","sequence":"additional","affiliation":[{"name":"Department of Emergency, Critical Care, and Disaster Medicine University of Miyazaki Hospital Miyazaki Miyazaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Otani","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine St. Luke's International Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai","family":"Taguchi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Kin\u2010ikyo Chuo Hospital Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8906-6230","authenticated-orcid":false,"given":"Takuya","family":"Shimane","sequence":"additional","affiliation":[{"name":"Department of Drug Dependence Research National Institute of Mental Health, National Center of Neurology and Psychiatry Kodaira Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoko","family":"Kyan","sequence":"additional","affiliation":[{"name":"Department of Clinical Toxicology Saitama Medical University Hospital Iruma\u2010gun Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Ministry of Health Labour and Welfare National Police Agency. 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