{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T10:15:01Z","timestamp":1771668901538,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3895,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenat. Diagn."],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1002\/pd.1197","type":"journal-article","created":{"date-parts":[[2005,7,20]],"date-time":"2005-07-20T12:17:36Z","timestamp":1121861856000},"page":"582-585","source":"Crossref","is-referenced-by-count":18,"title":["Precise prenatal diagnosis of tuberous sclerosis by sequencing the TSC2 gene"],"prefix":"10.1002","volume":"25","author":[{"given":"Aubrey","family":"Milunsky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Han","family":"Shim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masamichi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald K.","family":"Jaekle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori L.","family":"Bassett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Brumund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff M.","family":"Milunsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005]]},"reference":[{"key":"10.1002\/pd.1197-BIB1","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1086\/301705","volume":"62","author":"Au","year":"1998","journal-title":"Am J Hum Genet"},{"key":"10.1002\/pd.1197-BIB2","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1067\/S0022-3476(03)00494-3","volume":"143","author":"Bader","year":"2003","journal-title":"J Pediatr"},{"key":"10.1002\/pd.1197-BIB3","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/pd.55","volume":"21","author":"Benit","year":"2001","journal-title":"Prenat Diagn"},{"key":"10.1002\/pd.1197-BIB4","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1002\/pd.1970080805","volume":"8","author":"Chitayat","year":"1988","journal-title":"Prenat Diagn"},{"key":"10.1002\/pd.1197-BIB5","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1136\/jmg.20.4.303","volume":"20","author":"Crawford","year":"1983","journal-title":"J Med Genet"},{"key":"10.1002\/pd.1197-BIB6","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1515\/JPM.2002.022","volume":"30","author":"D'Addario","year":"2002","journal-title":"J Perinat Med"},{"key":"10.1002\/pd.1197-BIB7","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/0092-8674(93)90618-Z","volume":"75","author":"The European Chromosome 16 Tuberous Sclerosis Consortium","year":"1993","journal-title":"Cell"},{"key":"10.1002\/pd.1197-BIB8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/pd.825","volume":"24","author":"Fesslova","year":"2004","journal-title":"Prenat Diagn"},{"key":"10.1002\/pd.1197-BIB9","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1002\/pd.464","volume":"22","author":"Gamzu","year":"2002","journal-title":"Prenat Diagn"},{"key":"10.1002\/pd.1197-BIB10","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1055\/s-2007-994681","volume":"9","author":"Giocoia","year":"1992","journal-title":"Am J Perinatol"},{"key":"10.1002\/pd.1197-BIB11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.1991.tb37742.x","volume":"615","author":"Gomez","year":"1991","journal-title":"Ann N Y Acad Sci"},{"key":"10.1002\/pd.1197-BIB12","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/0002-9378(87)90079-2","volume":"156","author":"Gresser","year":"1987","journal-title":"Am J Obstet Gynecol"},{"key":"10.1002\/pd.1197-BIB13","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/0735-1097(95)80031-B","volume":"26","author":"Holley","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/pd.1197-BIB14","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s00246-003-0590-4","volume":"25","author":"Isaacs","year":"2004","journal-title":"Pediatr Cardiol"},{"key":"10.1002\/pd.1197-BIB15","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1086\/302381","volume":"64","author":"Jones","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1002\/pd.1197-BIB16","first-page":"48","volume":"3","author":"Pipitone","year":"2002","journal-title":"Ital Heart J"},{"key":"10.1002\/pd.1197-BIB17","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/pd.1970070606","volume":"7","author":"Platt","year":"1987","journal-title":"Prenat Diagn"},{"key":"10.1002\/pd.1197-BIB18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1469-1809.1994.tb01881.x","volume":"58","author":"Povey","year":"1994","journal-title":"Ann Hum Genet"},{"key":"10.1002\/pd.1197-BIB19","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1002\/pd.1970130902","volume":"13","author":"Revel","year":"1993","journal-title":"Prenat Diagn"},{"key":"10.1002\/pd.1197-BIB20","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1177\/088307389801301206","volume":"13","author":"Roach","year":"1998","journal-title":"J Child Neurol"},{"key":"10.1002\/pd.1197-BIB21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01403693","volume":"26","author":"Sonigo","year":"1996","journal-title":"Pediatr Radiol"},{"key":"10.1002\/pd.1197-BIB22","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0002-9149(03)00677-5","volume":"92","author":"Tworetzky","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1002\/pd.1197-BIB23","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1126\/science.277.5327.805","volume":"277","author":"van Slegtenhorst","year":"1997","journal-title":"Science"},{"key":"10.1002\/pd.1197-BIB24","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1136\/jmg.33.1.47","volume":"33","author":"Vrtel","year":"1996","journal-title":"J Med Genet"},{"key":"10.1002\/pd.1197-BIB25","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1749-6632.1991.tb37747.x","volume":"615","author":"Watson","year":"1991","journal-title":"Ann N Y Acad Sci"},{"key":"10.1002\/pd.1197-BIB26","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1093\/hmg\/6.13.2265","volume":"6","author":"Yates","year":"1997","journal-title":"Hum Mol Genet"},{"key":"10.1002\/pd.1197-BIB27","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1046\/j.1469-1809.1998.6230203.x","volume":"62","author":"Young","year":"1998","journal-title":"Ann Hum Genet"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1197","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/pd.1197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T22:03:00Z","timestamp":1625349780000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pd.1197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,7]]}},"URL":"https:\/\/doi.org\/10.1002\/pd.1197","relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}