{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:47:29Z","timestamp":1782604049037,"version":"3.54.5"},"reference-count":39,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2005,9,19]],"date-time":"2005-09-19T00:00:00Z","timestamp":1127088000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Conjoined twins are a rare and complex complication of monozygotic twinning, which is associated with high perinatal mortality. Early prenatal diagnosis of conjoined twins allows better counselling of the parents regarding the management options, including continuation of pregnancy with post\u2010natal surgery, termination of pregnancy or selective fetocide in case of a triplet pregnancy. With the introduction of high\u2010resolution and transvaginal ultrasound imaging, accurate prenatal diagnosis of conjoined twins is possible early in pregnancy. We have reviewed the medical literature on the early prenatal diagnosis of suspected conjoined twins using a MEDLINE search. Although first\u2010trimester diagnosis of conjoined twins is feasible, false\u2010positive cases are common before 10 weeks because, earlier in gestation, fetal movements are limited and monoamniotic twins may appear conjoined. As most parents opt for immediate termination of pregnancy at confirmation of the diagnosis, there are limited data on the prenatal follow\u2010up of conjoined twins. When the parents opt for conservative management, half of the fetuses die <jats:italic>in utero<\/jats:italic> and another 44% will die during the neonatal period. A detailed analysis of case reports where 3D imaging was used indicates that this modality does not improve on the diagnosis made by 2D ultrasound. Overall, very early prenatal diagnosis and first\u2010trimester 3D imaging provide very little additional practical medical information compared to the 11\u201314 weeks' ultrasound examination. Copyright \u00a9 2005 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.1267","type":"journal-article","created":{"date-parts":[[2005,9,19]],"date-time":"2005-09-19T11:18:56Z","timestamp":1127128736000},"page":"820-826","source":"Crossref","is-referenced-by-count":80,"title":["First\u2010trimester diagnosis of conjoined 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