{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T22:28:15Z","timestamp":1758925695500},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T00:00:00Z","timestamp":1166745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Our objective was to identify the clinical consequences of deep\u2010hidden anastomoses that occur underneath the placental surface.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twelve placentae that underwent intrauterine laser ablation of placental anastomoses for twin\u2013twin transfusion syndrome (TTTS) and 14 non\u2010TTTS controls were investigated for deep\u2010hidden anastomoses. Additionally, we investigated the inter\u2010twin haemoglobin differences as an indicator for fetofetal transfusion. Placentae were divided into four groups: TTTS placentae without residual chorionic\u2010plate anastomoses without deep\u2010hidden anastomoses (group 1) and with deep\u2010hidden anastomoses (group 2), and non\u2010TTTS placentae with chorionic\u2010plate anastomoses without deep\u2010hidden anastomoses (group 3) and with deep\u2010hidden anastomoses (group 4).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Deep\u2010hidden anastomoses were identified in 58% (7\/12) of the TTTS placentae after laser surgery and in 64% (9\/14) of the non\u2010TTTS placentae. Groups 1 and 2 had equal inter\u2010twin haemoglobin differences: medians 1.4 and 1.2 gr\/dL, respectively (<jats:italic>p<\/jats:italic> = 0.48). In group 3, the median inter\u2010twin haemoglobin difference without deep\u2010hidden anastomoses was 2.6 gr\/dL (group 3) and with deep\u2010hidden anastomoses (group 4) it was 5.1 gr\/dL (<jats:italic>p<\/jats:italic> = 0.26).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both comparisons imply that deep\u2010hidden anastomoses did not cause any additional increase in Hb difference. In conclusion, haematological and additional hemodynamical analysis show that deep\u2010hidden anastomoses are likely to occur without any clinical consequences. Copyright \u00a9 2006 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.1652","type":"journal-article","created":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T09:51:49Z","timestamp":1166781109000},"page":"233-239","source":"Crossref","is-referenced-by-count":23,"title":["Deep\u2010hidden anastomoses in monochorionic twin placentae are harmless"],"prefix":"10.1002","volume":"27","author":[{"given":"Jeroen P. H. M.","family":"van den Wijngaard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Lopriore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra M. A.","family":"van der Salm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arty H. P.","family":"Schaap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank P. H. A.","family":"Vandenbussche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco C.","family":"DeRuiter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J. C.","family":"van Gemert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)36109-9"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(71)90055-4"},{"key":"e_1_2_1_4_1","first-page":"130","volume-title":"On Growth and Form","author":"D'Arcy WT","year":"1961"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2004.06.010"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200304000-00013"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.062"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2006.01.010"},{"key":"e_1_2_1_9_1","article-title":"Assessment of feto\u2010fetal transfusion flow through placental arterio\u2010venous anastomoses in a unique case of twin\u2010to twin transfusion syndrome","author":"Lopriore E","year":"2006","journal-title":"Placenta"},{"key":"e_1_2_1_10_1","first-page":"45","volume-title":"Monochorionic Twin Placentas, Clinical Outcome and Computer Modelling of a High\u2010Risk Pregnancy. Multiple Pregnancy","author":"Nikkels PGJ","year":"2006"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01676-1"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2001.0758"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(98)90009-1"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200104000-00015"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2004.04.007"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1652","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1652","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T09:59:49Z","timestamp":1700042389000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12,22]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1002\/pd.1652"],"URL":"https:\/\/doi.org\/10.1002\/pd.1652","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12,22]]}}}