{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T22:08:58Z","timestamp":1770502138651,"version":"3.49.0"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,2,23]],"date-time":"2007-02-23T00:00:00Z","timestamp":1172188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the attitudes of women from two different ethnic backgrounds to prenatal testing for a range of conditions, and to see if \u201cclusters\u201d of attitudes to different conditions could be identified, for which prenatal testing might be offered as a package.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four hundred and twenty white and Pakistani women living in the UK were surveyed about their attitudes to prenatal testing and termination for 30 different fetal conditions. All participants had recently had a baby.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pakistani women held more favourable attitudes to prenatal testing, but less favourable attitudes to termination than their white counterparts. Both groups were most in favour of termination for the same four conditions: anencephaly, trisomy 13 or 18, quadriplegia, Duchenne muscular dystrophy. The rank ordering of conditions was also similar. Only 4% of Pakistani and 2% of white women wanted no prenatal testing at all. Fewer than a quarter of participants would consider a termination of pregnancy for 85% of the conditions, but only 25% of Pakistani women and 6% of white women would consider termination for none of the conditions. More advanced statistical analyses were used to measure how closely associated the 30 conditions were in respondents' answers. These analyses identified a principal dimension, reflecting the overall perceived seriousness of the conditions, and a cluster of severely disabling conditions\u2014anencephaly, trisomy 13 or 18, quadriplegia, Duchenne muscular dystrophy, and severe learning difficulties\u2014which stood out from the rest. Even within this cluster there remained a considerable amount of individual variation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Women in the study wanted to make up their own minds about the conditions that to them merited testing or termination. These findings have implications for obtaining informed consent. Copyright \u00a9 2007 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.1701","type":"journal-article","created":{"date-parts":[[2007,2,23]],"date-time":"2007-02-23T11:08:46Z","timestamp":1172228926000},"page":"419-430","source":"Crossref","is-referenced-by-count":42,"title":["Attitudes to prenatal testing and termination of pregnancy for fetal abnormality: a comparison of white and Pakistani women in the UK"],"prefix":"10.1002","volume":"27","author":[{"given":"Jenny","family":"Hewison","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josephine M.","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenaz","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard S.","family":"Cuckle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Hirst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare","family":"Hucknall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim G.","family":"Thornton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,23]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1258\/0969141053908258"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1391"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(200005)20:5<378::AID-PD815>3.0.CO;2-7"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.76"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(98)00261-5"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1352\/0895-8017(2000)105<0001:RTPTRO>2.0.CO;2"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1162\/152651603322781648"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000116212.89556.42"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200103)21:3<159::AID-PD20>3.0.CO;2-V"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320410307"},{"key":"e_1_2_1_12_1","volume-title":"The User's Guide to Multidimensional Scaling","author":"Coxon APM","year":"1982"},{"issue":"3","key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta4030","article-title":"Screening for sickle cell disease and thallassaemia: a systematic review with supplementary research","volume":"4","author":"Davies SC","year":"2000","journal-title":"Health Technol Assess"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","unstructured":"EvansMI SobieckiMA KrivcheniaELet al. 1996. 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