{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T19:44:52Z","timestamp":1725565492855},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,17]],"date-time":"2005-11-17T00:00:00Z","timestamp":1132185600000},"content-version":"vor","delay-in-days":8540,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1982,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The Antley\u2010Bixler syndrome is characterized by multiple skeletal fusions including humero\u2010radial synostosis, anterior bowing of the femora, cardiac and renal malformations and a high incidence of early postnatal lethality. In the pregnancy of a mother who had previously given birth to a child with the Antley\u2010Bixler syndrome, prenatal ultrasound diagnosis was performed at 17 and 20 weeks. Fixed flexion of about 80\u00b0 in both elbows was seen together with humero\u2010radial synostosis and bowing of the ulnae. The fetus performed jerky cranio\u2010caudal movements in its shoulders, but did not, during five hours of real\u2010time observation, move at all in the elbows. Mild anterior bowing of the femora was also observed. The pregnancy was terminated at 21 weeks, and radiological examination of the female fetus confirmed the above mentioned findings including complete bilateral humero\u2010radial synostosis. She also had cardiac and renal malformations. An ultrasound diagnosis of syndromes which have humero\u2010radial synostosis as one feature is possible. Immobility and flexion in the elbows during a long period is probably the essential diagnostic finding.<\/jats:p>","DOI":"10.1002\/pd.1970020311","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:22:30Z","timestamp":1172964150000},"page":"219-223","source":"Crossref","is-referenced-by-count":14,"title":["Prenatal ultrasound detection of humero\u2010radial synostosis in a case of antley\u2010bixler syndrome"],"prefix":"10.1002","volume":"2","author":[{"given":"G.","family":"Savoldelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schinzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,17]]},"reference":[{"issue":"2","key":"e_1_2_1_2_1","first-page":"397","article-title":"Trapezoidocephaly, midfacial hypoplasia and cartilage abnormalities with multiple synostosis and skeletal fractures","author":"Antley R. M.","year":"1975","journal-title":"Birth Defects"},{"issue":"2","key":"e_1_2_1_3_1","first-page":"12","article-title":"Case report 33","author":"Bass H. N.","year":"1975","journal-title":"Syndrome Identification"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320070322"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00273020"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00696013"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32646-1"},{"issue":"2","key":"e_1_2_1_8_1","first-page":"17","article-title":"Case report 49","author":"Majewski F.","year":"1976","journal-title":"Syndrome Identification"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(80)90252-5"},{"key":"e_1_2_1_10_1","first-page":"243","article-title":"A case of multiple skeletal anomalies, ectodermal dysplasia, and severe growth and mental retardation","volume":"35","author":"Schinzel A.","year":"1980","journal-title":"Helv. paediatr. Acta"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","unstructured":"Schinzel A. Savoldelli G. Briner J. Figg P. Massini C.(1982).The Antley\u2010Bixler syndrome in sisters: A term newborn and a prenatally diagnosed fetus.Am. J. Med. Genet. in press.","DOI":"10.1002\/ajmg.1320140119"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32640-0"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970020311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970020311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T05:38:53Z","timestamp":1699767533000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970020311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,7]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1982,7]]}},"alternative-id":["10.1002\/pd.1970020311"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970020311","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,7]]}}}