{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:50:27Z","timestamp":1768585827433,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":8087,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1983,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pure fetal blood has been aspirated <jats:italic>in utero<\/jats:italic> from the umbilical vein near the placental insertion of the cord using a twenty gauge needle under ultrasound guidance.<\/jats:p><jats:p>Sixty\u2010six samples were taken on 63 pregnancies between 17 and 32 weeks of gestation. One to two millilitres of blood can be obtained easily without amniotic fluid dilution or contamination by maternal blood, as confirmed by the measurements of the mean corpuscular volume, the histogram distribution of the red blood cells and the hematocrit. In all cases the Kleihauer test and isoelectrofocusing of the hemoglobins were performed. Coagulation factors were also studied in 60 cases.<\/jats:p><jats:p>In 17 cases a medical abortion was voluntarily induced after the procedure, and the follow\u2010up was normal during the observation period after sampling. In the other cases, pregnancies have continued normally and twelve healthy babies have already been born.<\/jats:p>","DOI":"10.1002\/pd.1970030402","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:32:27Z","timestamp":1172964747000},"page":"271-277","source":"Crossref","is-referenced-by-count":155,"title":["Fetal blood sampling via the umbilical cord using a needle guided by ultrasound report of 66 cases"],"prefix":"10.1002","volume":"3","author":[{"given":"Fernand","family":"Daffos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martine","family":"Capella\u2010Pavlovsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Forestier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1085","article-title":"Cytological differentiation of haemoglobin","volume":"29","author":"Betke K.","year":"1968","journal-title":"Bibl. Haematol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(73)90033-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.19.2.81"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1182\/blood.V56.6.1092.1092","article-title":"Prenatal diagnosis of hemoglobinopathies: comparison of the results obtained by isoelectric focusing and by chromatography of radioactive globin chains","volume":"56","author":"Dubart A.","year":"1980","journal-title":"Blood"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6109.350"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197405092901908"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0002-9378(16)32794-6","article-title":"Pure fetal blood from the umbilical cord obtained at fetoscopy. Experience with 125 consecutive cases","volume":"138","author":"Mackenzie I. Z.","year":"1980","journal-title":"Am. J. Obst. Gynecol."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6139.728"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)91928-7"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(73)90532-2"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970030402","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970030402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T05:51:39Z","timestamp":1697781099000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970030402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["10.1002\/pd.1970030402"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970030402","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,10]]}}}