{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T23:17:46Z","timestamp":1698016666030},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":7690,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1984,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A further case of trisomy 20 mosaicism found at amniocentesis is presented. Pregnancy was terminated, the fetus showed facial dysmorphia and minor cardial and renal anomalies. 19 published reports of true trisomy 20 mosaicism at amniocentesis are reviewed. Five pregnancies resulted in obviously normal newborns. The significance of mostly minor anomalies found at autopsy of 7 fetuses remains unclear. With regard to genetic counselling the significance of trisomy 20 mosaicism is summarized as follows: (1) true trisomy 20 mosaicism in amniotic fluid cells reflects mosaicism of the fetus; (2) severe malformation is not a major feature of trisomy 20 mosaicism; (3) the risk of mental retardation is still undetermined, due to limited experience. However, there is no definite proof that the condition is harmful at all.<\/jats:p>","DOI":"10.1002\/pd.1970040604","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:48:45Z","timestamp":1172965725000},"page":"411-419","source":"Crossref","is-referenced-by-count":16,"title":["Trisomy 20 mosaicism"],"prefix":"10.1002","volume":"4","author":[{"given":"P.","family":"Miny","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.\u2010H.","family":"Pawlowitzki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00303028"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970020312"},{"key":"e_1_2_1_4_1","first-page":"3","article-title":"Le clonage des cellules du liquide amniotique, aide dans I'int\u00e9rpretation des mosaiques chromosomiques en diagnostic pr\u00e9natal","volume":"22","author":"Bou\u00e9 J.","year":"1979","journal-title":"Ann. 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Cited from Bou\u00e9 et al. (1979)."},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1979.tb01776.x"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)90276-2"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1976.tb01595.x"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1979.tb01756.x"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197804001-00556"},{"key":"e_1_2_1_25_1","unstructured":"Plotz E. J. Hansmann M. Niesen M. Schwanitz G.(1981) Pr\u00e4natale Diagnostik eines Mosaiks Trisomie 20 genetische Beratung der Familie und Untersuchungen des morphologisch auff\u00e4lligen Probanden.The German Society for Anthropology and Human Genetics 17th meeting G\u00f6ttingen."},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1978.tb04245.x"},{"key":"e_1_2_1_27_1","first-page":"249","article-title":"Mosaicism in amniotic fluid cell cultures","volume":"3","author":"Rudd N. L.","year":"1977","journal-title":"Birth Defects: Original Article Series"},{"key":"e_1_2_1_28_1","volume-title":"Catalogue of Unbalanced Chromosome Aberrations in Man","author":"Schinzel A.","year":"1984"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)91310-6"},{"key":"e_1_2_1_30_1","first-page":"97A","article-title":"Mosaicism for trisomy 20 in cultured amniotic fluid cells (abstract)","volume":"30","author":"Vinson P.","year":"1978","journal-title":"Am. J. Hum. 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