{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T22:08:09Z","timestamp":1698358089702},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":7509,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1985,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Amniocentesis was performed in view of a paternal balanced chromosomal rearrangement t(4;20)(p16;p12), inv(18)(p11q11). The pregnancy was complicated by severe oligohydramnios. The fetal karyotype was unbalanced: 46XX, der(4), t(4;20)(p16;p12), inv(18) (p11q11)pat., thus resulting in partial trisomy 2Op and monosomy 4p. In addition, the amniotic fluid alpha\u2010fetoprotein (AFP) became increasingly elevated with gestational age. The pregnancy was terminated at 25 weeks. The fetus presented with typical facial dysmorphic features, unilateral cleft lip and palate, severe renal hypoplasia, consistent with the 4p\u2010 (Wolf\u2010Hirschhorn) syndrome.<\/jats:p>","DOI":"10.1002\/pd.1970050308","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:58:40Z","timestamp":1172966320000},"page":"209-214","source":"Crossref","is-referenced-by-count":10,"title":["Prenatal diagnosis and fetal pathology of partial trisomy 20p\u2013monosomy 4p resulting from paternal translocation"],"prefix":"10.1002","volume":"5","author":[{"given":"E.","family":"Vamos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Pratola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Van Regemorter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Freund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Flament\u2010Durand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Rodesch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.16.3.229"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.14.3.232"},{"key":"e_1_2_1_4_1","first-page":"34","volume-title":"Prenatal Diagnosis: Proceedings of the 3rd European Conference on Prenatal Diagnosis of Genetic Disorders","author":"Bou\u00e9 A.","year":"1979"},{"key":"e_1_2_1_5_1","first-page":"41","article-title":"Simultaneous trisomy 10q24\u2192qter and monosomy 4p16: an example of epistasis at the chromosome level","volume":"24","author":"Cantu J. M.","year":"1981","journal-title":"Ann. Genet."},{"key":"e_1_2_1_6_1","first-page":"77","article-title":"Familial trisomy 20p. Five cases and two camers in three generations. A review","volume":"20","author":"Centerwall W.","year":"1977","journal-title":"Ann. Genet."},{"key":"e_1_2_1_7_1","first-page":"54","article-title":"Partial trisomy 20","volume":"24","author":"Delicado A.","year":"1981","journal-title":"Ann. 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El Khazen N. Jeanty Ph. Jkvi S. Picard C. RodeschF.Pathological pregnancies: results of amniotic fluid studies and fetal out\u2010come in preparation."}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970050308","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970050308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T13:03:40Z","timestamp":1697807020000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970050308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,5]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1985,5]]}},"alternative-id":["10.1002\/pd.1970050308"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970050308","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,5]]}}}