{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:50:36Z","timestamp":1757703036869},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":7264,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1986,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Second trimester amniocentesis has traditionally been utilized for prenatal genetic diagnosis. Chorionic villi sampling (CVS) is presently offered as an alternative. The occurrence of fetomaternal bleed (FMB) during CVS could increase the rate of post sampling abortion and, additionally, be of significance in patients at risk for isoimmunization. Detection and quantitation of FMB can be accomplished by the determination of changes in maternal serum alpha\u2010fetoprotein (MSAFP) before and after CVS.<\/jats:p>","DOI":"10.1002\/pd.1970060110","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T19:21:35Z","timestamp":1172949695000},"page":"69-73","source":"Crossref","is-referenced-by-count":11,"title":["Chorionic villi sampling changes maternal serum alpha\u2010fetoprotein"],"prefix":"10.1002","volume":"6","author":[{"given":"Federico G.","family":"Mariona","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupi","family":"Bhatia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank N.","family":"Syner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick","family":"Koppitch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4809(72)90082-1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)92373-4"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6073.1377"},{"key":"e_1_2_1_5_1","first-page":"60","article-title":"Fetomaternal bleeding following diagnostic amniocentesis","volume":"60","author":"Lele A. S.","year":"1982","journal-title":"Obstet. Gynecol."},{"key":"e_1_2_1_6_1","first-page":"23","article-title":"Changes in maternal serum alpha\u2010fetoprotein levels associated with chorionic villi sampling","volume":"8","author":"Mariona F. G.","year":"1985","journal-title":"J. Clin. Immunoassay"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1984.12.4.179"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00274761"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970040308"},{"key":"e_1_2_1_10_1","unstructured":"Symposium(1984).Chorionic villus sampling: something new in prenatal diagnosis Contemporary Ob\/Gyn December 118\u2013138."},{"key":"e_1_2_1_11_1","first-page":"1245","article-title":"The pathogenesis and prevention of Rh immunization","volume":"97","author":"Zipursky A.","year":"1967","journal-title":"Can. Med. Assoc. J."}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970060110","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970060110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T23:53:51Z","timestamp":1697932431000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970060110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1986,1]]}},"alternative-id":["10.1002\/pd.1970060110"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970060110","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,1]]}}}