{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T08:02:22Z","timestamp":1750492942707},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,5]],"date-time":"2005-12-05T00:00:00Z","timestamp":1133740800000},"content-version":"vor","delay-in-days":6882,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1987,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Using information derived from the voluntary system of notification of congenital malformations in England and Wales, the birth prevalence of anencephaly and spina bifida was estimated to have declined by 80 per cent from 31.5 to 6.2 per 10 000 between 1964\u20131972 and 1985. Over the same period, notified terminations of pregnancy with a suspected fetal central nervous system abnormality increased from less than 1 per cent to 56 per cent of neural tube defect births and central nervous system terminations combined, accounting for 31 per cent of the decline in births. Routinely collected national statistics provide a method for monitoring the impact of screening for open neural tube defects. However because they are incomplete and lack detail an alternative method of monitoring is needed. This paper includes an outline of such a method, together with the results of a pilot study designed to assess the feasibility of monitoring screening in the Oxford Region.<\/jats:p>","DOI":"10.1002\/pd.1970070205","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T00:40:24Z","timestamp":1172968824000},"page":"91-99","source":"Crossref","is-referenced-by-count":39,"title":["The impact of screening for open neural tube defects in England and Wales"],"prefix":"10.1002","volume":"7","author":[{"given":"Howard","family":"Cuckle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Wald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,5]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Late Abortions in England and Wales. Report of a National Confidential Study","author":"Alberman E.","year":"1984"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.289.6453.1182"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a071849"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.38.4.296"},{"key":"e_1_2_1_6_1","unstructured":"Office of Population Censuses and Surveys(1978\u20131986).Abortion Statistics Series AB Nos 1\u201012."},{"key":"e_1_2_1_7_1","unstructured":"Office of Population Censuses and Surveys(1978\u20131986).Birth Statistics Series FM 1 Nos 1\u201312."},{"key":"e_1_2_1_8_1","unstructured":"Office of Population Censuses and Surveys(1983\u20131986).Congenital Malformation Statistics Series MB3 Nos 1\u20133."},{"key":"e_1_2_1_9_1","unstructured":"Rogers S. C. Weatherall J. A. C.(1976). Anencephalus spina bifida and congenital hydrocephalus. England and Wales 1964\u20131972. Office of Population Censuses and Surveys Studies on Medical and Population Subjects No. 32."},{"key":"e_1_2_1_10_1","first-page":"321","article-title":"Amniotic fluid acetyl\u2010cholinesterase electrophoresis as a secondary test in the diagnosis of anencephaly and open spina bifida in early pregnancy","year":"1981","journal-title":"Lancet"},{"key":"e_1_2_1_11_1","first-page":"1323","article-title":"Maternal serum alpha\u2010fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy","year":"1977","journal-title":"Lancet"},{"key":"e_1_2_1_12_1","first-page":"652","article-title":"Amniotic fluid alpha\u2010fetoprotein measurement in antenatal diagnosis of anencephaly and open spina bifida in early pregnancy","year":"1979","journal-title":"Lancet"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1977.tb12599.x"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)90742-4"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)91823-1"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1982.tb04663.x"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6185.331"},{"key":"e_1_2_1_18_1","first-page":"85","article-title":"A review of some effects of recent medical practices in reducing the number of children born with congenital abnormalities","volume":"14","author":"Weatherall J. A. C.","year":"1982","journal-title":"Health Trends"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970070205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970070205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T05:52:56Z","timestamp":1697867576000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970070205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1987,2]]}},"alternative-id":["10.1002\/pd.1970070205"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970070205","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,2]]}}}